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Talya Wasserman-Bartov on Muck Rack

Talya Wasserman-Bartov

As seen in: Cell Reports Medicine
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Articles

Lymphodepleting chemotherapy potentiates neoantigen-directed T cell therapy by enhancing antigen presentation

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By Shira Sagie, Tomer Babu, Chen Weller, Ido Livneh, Nele P Quast, Nofar Gumpert, Alina S. Shomuradova, Ronen Levy, Dmitry Malko, Michal Alon, Franco Hessling Herrera, Mikhail Kutuzov, Mirie Zerbib, Polina Greenberg, Gil Benedek, Yishai Levin, Chani Stossel, Iris Kamer, Talia Golan, Roni Oren, Merav D. Shmueli, Osnat Bartok, Jair Bar, Jonathan Cohen, Omer Dushek, Charlotte M. Deane, Yardena Samuels, Claire Tabachnik, Matthew I. Raybould, Adi Alfia, Talal Ben Lulu, Talya Wasserman-Bartov
| Cell Reports Medicine Verified
Results Utilizing our previously developed data-driven pipeline,26 we prioritized candidate neoantigens from The Cancer Genome Atlas (TCGA) lung cancer dataset and identified the KRAS.G12V-HLA-A∗03:01 combination as a leading candidate. This HLA-mutation combination is found in approximately 94,000 patients worldwide (Figure 1A; Table S1).
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