Tammaryn Lashley on Muck Rack

Tammaryn Lashley

As seen in: Color Research & Application, Nature, Wiley Online Library, MDPI, ACS Publications, Cell Press, Cell Reports
Professor of Neuroscience UCL. Wife/ Mother of three and negotiating the world of special educational needs
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Articles

Early oligodendrocyte dysfunction signature in Alzheimer’s disease: Insights from DNA methylomics and transcriptomics

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By Katherine Fodder, Hannah Smith, Umran Yaman, Ignazio Piras, Megha Murthy, John Hardy, Tammaryn Lashley, Rohan de Silva, Dervis Salih, Conceição Bettencourt
| Nature Verified
Abstract Much research into the aetiology of Alzheimer’s disease (AD) has focused on neuronal cell types, while studies on the contribution of glial cells, particularly oligodendrocytes (OLGs), are only starting to emerge. Altered brain DNA methylation, an epigenetic modification that provides the interplay between genetics and environmental cues to tightly regulate gene expression, is well documented in AD. Yet, cell-type-specific investigations remain limited.
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Widespread hnRNP K Mislocalisation Suggests Differential Neuronal Vulnerability in the Neurodegenerative and Ageing Human Brain

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By Xinwa Jiang, Christina E. Toomey, Tammaryn Lashley
| Wiley Online Library Verified
1 Introduction Heterogeneous nuclear ribonucleoproteins (hnRNPs) are a group of RNA-binding proteins (RBPs) that play crucial roles in the regulation of mRNA processing and metabolism. They function through dynamic interactions with RNA molecules and other RBPs within RNA-protein complexes [1]. Differing from other RBPs, such as SR splicing factors and messenger RNPs (mRNPs), hnRNPs follow a unique nomenclature that extends alphabetically from A to U [1].
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Author Correction: Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer’s disease - Nature Neuroscience

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By Sebastiaan De Schepper, Judy Z. Ge, Annerieke Sierksma, Gerard Crowley, Dylan Garceau, Christina E. Toomey, Dimitra Sokolova, Javier Rueda-Carrasco, Sun-Hye Shin, Jung-Seok Kim, Thomas E. Childs, Tammaryn Lashley, Jemima J. Burden, Michael Sasner, Carlo Sala Frigerio, Steffen Jung, Soyon Hong, Laís S. S. Ferreira
| Nature Verified
Correction to: Nature Neuroscience https://doi.org/10.1038/s41593-023-01257-z, published online 6 February 2023. A clerical error occurred during the submission of the final accepted version of this paper, in which draft versions of the source data files were mistakenly uploaded instead of the final, cross-checked versions. As a result, discrepancies arose between the published, correct figure data points and the outdated source data files for 12 out of the 21 figures.
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