Teresa Chin

SHARE THIS POST By Teresa Chin As a parent, I’ve always believed that the best family holidays are the ones that let everyone, from the littlest to the oldest, feel like they belong. And that’s exactly what we found during our recent family getaway to Club Med Phuket, now home to the brand-new Lai Thai Family Oasis, the first of its kind in the Asia Pacific region.

Results We crossed a previously generated Stxbp1tm1a/+ mouse (Chen et al., 2020) with a Flp recombinase germline deleter mouse to create a new Stxbp1 flox allele (tm1c), in which exon 7 is flanked by two loxP sites (Fig. 1A). Heterozygous (Stxbp1f/+) and homozygous (Stxbp1f/f) flox mice are viable and fertile. Western blots showed that Stxbp1f/+ and Stxbp1f/f mice had similar Stxbp1 protein levels to their WT littermates at P0 and 3 months of age (Fig.

GABAergic/glycinergic and glutamatergic neurons mediate distinct neurodevelopmental phenotypes of STXBP1 encephalopathy Joo Hyun Kim, Wu Chen, Eugene S. Chao, Armando Rivera, Heet Naresh Kaku, Kevin Jiang, Dongwon Lee, Hongmei Chen, Jaimie M. Vega, Teresa V. Chin, Kevin Jin, Kelly T. Nguyen, Sheldon S. Zou, Zain Moin, Shawn Nguyen, Mingshan Xue (薛名杉) Journal of Neuroscience 15 February 2024, e1806232024; DOI: 10.1523/JNEUROSCI.1806-23.2024