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Tianying Tong

As seen in: Cell Reports, Cell Metabolism
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Articles

Microbial metabolite FAD mobilizes adipocyte lipid remodeling to enhance cancer immunotherapy efficacy

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By Tianying Tong, Xiaowen Huang, Lingxi Li, Muni Hu, Xiaoqiang Zhu, Beiyao Zhu, Yanru Ma, Lijun Ning, Yi Jiang, Yue Zhang, Yilu Zhou, Zhenyu Wang, Jinmei Ding, Ying Zhao, Baoqin Xuan, Youwei Zhang, Xiuying Xiao, Jing-Yuan Fang, Jie Hong, Yan Yin, Fenglin Liu, Haoyan Chen
| Cell Metabolism Verified
Keywords gut microbiota immunotherapy adipocyte obesity microbial metabolite unsaturated fatty acids Get full text access Log in, subscribe or purchase for full access. References 1. Kwon, S.Y. ∙ Thi-Thu Ngo, H. ∙ Son, J. ... Exploiting bacteria for cancer immunotherapy Nat. Rev. Clin. Oncol. 2024; 21:569-589 2. Ratiner, K. ∙ Ciocan, D. ∙ Abdeen, S.K. ... Utilization of the microbiome in personalized medicine Nat. Rev. Microbiol. 2024; 22:291-308 3. Trefny, M.P. ∙ Kroemer, G. ∙ Zitvogel, L. ...
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Optimizing anti-PD-1/PD-L1 therapy efficacy and fecal microbiota transplantation donor selection through gut mycobiome-based enterotype

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By Muni Hu, Xiaoqiang Zhu, Xiaowen Huang, Li Hua, Xiaolin Lin, Hangyu Zhang, Ye Hu, Tianying Tong, Lingxi Li, Baoqin Xuan, Ying Zhao, Yilu Zhou, Jinmei Ding, Yanru Ma, Yi Jiang, Lijun Ning, Yue Zhang, Zhenyu Wang, Jing-Yuan Fang, Youwei Zhang, Xiuying Xiao, Jie Hong, Huimin Chen, Jiantao Li, Haoyan Chen
| Cell Reports Verified
Keywords immunotherapy gut microbiome gut mycobiome enterotype fecal microbiota transplantation Research topic(s) CP: Microbiology Introduction Immunotherapy has demonstrated significant success in treating various hematological and metastatic solid malignancies.1,2,3,4 The impact of the gut microbiome on therapeutic responses has been validated through numerous clinical and preclinical trials.5 Ongoing investigations in gut microbiome profiling have opened avenues for its potential as a...
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Interplay between gut microbial communities and metabolites modulates pan-cancer immunotherapy responses

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By Xiaoqiang Zhu, Muni Hu, Xiaowen Huang, Lingxi Li, Xiaolin Lin, Xiaoyan Shao, Jiantao Li, Xiaoyue Du, Xinjia Zhang, Rongrong Sun, Tianying Tong, Yanru Ma, Lijun Ning, Yi Jiang, Yue Zhang, Yuqi Shao, Zhenyu Wang, Yilu Zhou, Jinmei Ding, Ying Zhao, Baoqin Xuan, Hongyang Zhang, Youwei Zhang, Jie Hong, Jing-Yuan Fang, Xiuying Xiao, Bo Shen, Songbing He, Haoyan Chen
| Cell Metabolism Verified
Keywords immunotherapy gut microbiome metabolomics enterotype phenylacetylglutamine fecal microbiota transplantation Introduction Cancer immunotherapy holds great promise in the treatment of cancer by harnessing the power of the immune system.1 Various strategies are employed, including antibodies targeting specific proteins such as cytotoxic T lymphocyte protein 4 (CTLA-4), programmed cell death protein 1 (PD-1), and programmed death ligand 1 (PD-L1), known as immune checkpoints.2 While...
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