Wei-Xing Zong

Abstract SERPINB3 or SCCA1, a member of the serine proteinase inhibitor family, is frequently overexpressed in multiple malignancies, including lung adenocarcinoma (LUAD). However, its molecular mechanisms and endogenous substrates in lung cancer remain poorly characterized. Here, we identified SUMO-specific proteinase 3 (SENP3) as a novel direct interaction partner and functional target of SERPINB3 in LUAD.

AhR aryl-hydrocarbon receptor BBP benzyl butyl phthalate BPA bisphenol A BPF bisphenol F BPS bisphenol S CDP cytidine diphosphate CTP cytidine triphosphate DBP dibutyl phthalate DDT dichlorodiphenyltrichloroethane DM diabetes mellitus EDCs endocrine-disrupting compounds ER estrogen receptor MS mass spectrometry NHANES National Health and Nutrition Examination Survey NMR nuclear magnetic resonance PCBs polychlorinated biphenyls PFAA plasma-free amino acid PFAS per- and polyfluoroalkyl...