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Autism and Parkinsonism-Terminology and Confounding-Reply
In Reply We thank the Gros et al for their careful reading of our study.1 Parkinson disease (PD) before age 50 years is very rare, even among individuals with autism spectrum disorder (ASD). No direct clinical implications should hence be made from the study, and results should be interpreted cautiously due to observational nature of the study. Our study should be interpreted in light of the critical research gaps surrounding both PD and ASD.
Risk of Parkinson Disease in Individuals With Autism Spectrum Disorder
Supplement 1. eTable 2. Pattern of Missing Values in Individuals With Missing Data eTable 3. Characteristics of 208,601 Individuals With Missing Data eTable 4. Age-Specific Rate and Relative Risk of PD for ASD and Non-ASD eTable 5. Age-Specific Rate and Relative Risk of PD for Gestational Age Categories eTable 6. Distribution of 3-Level ICD Codes for PD Diagnosis Over the study Period eTable 7. Risk of Idiopathic PD for Individuals Diagnosed With ASD, Adjusting for Antipsychotic Use eTable 8.
Association between parental psychiatric disorders and risk of offspring autism spectrum disorder: a Swedish and Finnish population-based cohort study
Summary Roughly more than one in six adults worldwide suffer from psychiatric conditions. Sporadic studies have associated parental psychiatric disorders with autism spectrum disorder in offspring. Comprehensively examining the association between parental psychiatric disorders and offspring autism spectrum disorder is needed to guide health policies, and to inform etiologic studies. We included all children born in Sweden and Finland 1997–2016.
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