Weize Wang
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Articles by Weize Wang
SERPINB3 enhances NPM1 sumoylation via inhibiting SENP3’s activity and promotes lung tumorigenesis - Cell Death & Disease
Abstract SERPINB3 or SCCA1, a member of the serine proteinase inhibitor family, is frequently overexpressed in multiple malignancies, including lung adenocarcinoma (LUAD). However, its molecular mechanisms and endogenous substrates in lung cancer remain poorly characterized. Here, we identified SUMO-specific proteinase 3 (SENP3) as a novel direct interaction partner and functional target of SERPINB3 in LUAD.
Cavity Structure Evolution Based on Asymmetric Diffusion for Efficient Electromagnetic Wave Absorption
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm72275-sup-0001-SuppMat.docx21.9 MB Supporting Information References 1, , , , , , , Adv. Mater. 2025, 37, 2501302. 2, , , , , , Small Struct. 2023, 4, 2200219. 3, , , , , , , , Chem. Eng. J. 2025, 520, 165960. 4, , , , , , Carbon 2025, 235, 120095. 5, , , , , , , , , , , Nat. Commun. 2024, 15, 1497. 6, , , , , , , , Adv. Funct. Mater. 2025, 202512806. 7, , , , , , , , , , Chem. Eng. J. 2025, 519, 165016.
Structural insights into cholesterol sensing by the LYCHOS-mTORC1 pathway - Nature Communications
Abstract The lysosomal cholesterol sensor LYCHOS regulates mTORC1 signaling by coupling cholesterol sensing to GATOR1-Rag GTPase modulation, yet its structural mechanisms remain unclear. Here we report six cryo-electron microscopy structures of human LYCHOS, depicting five distinct states. These are categorized into a contracted state when complexed with a sufficient amount of the cholesterol analogue cholesteryl hemisuccinate (CHS), and an expanded state when CHS is deficient.
Mechanistic Insights Into the Assembly of Functional CRL3 Dimeric Complexes
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description bies202400175-sup-0001-SuppMat.pdf891.5 KB Supporting information References 1 and , “Ubiquitination of Non-Protein Substrates,” Trends in Cell Biology 33 (2023): 991–1003, https://doi.org/10.1016/j.tcb.2023.03.014.
Synergistic activation of the human phosphate exporter XPR1 by KIDINS220 and inositol pyrophosphate - Nature Communications
Abstract Inorganic phosphate (Pi) is essential for life, and its intracellular levels must be tightly regulated to avoid toxicity. XPR1, the sole known phosphate exporter, is critical for maintaining this balance. Here we report cryo-EM structures of the human XPR1-KIDINS220 complex in substrate-free closed and substrate-bound outward-open states, as well as an XPR1 mutant in a substrate-bound inward-facing state.
Extending interfacial toughness and thermal cycling lifetime of thermal barrier coatings via interfacial 3D pattern
Supporting Information Filename Description jace20254-sup-0001-SuppMat.docx179.4 KB Supporting Information REFERENCES 1, , , , , , et al. Effect of high-temperature infrared emissivity on thermal cycling performance of magnetoplumbite-type thermal barrier coatings under thermal gradient condition. J Eur Ceram Soc. 2024; 44(1): 448–59. 2, , . Ceramic materials for thermal barrier coatings. J Eur Ceram Soc. 2004; 24(1): 1–10. 3, .
Paving the Way for SQIsign: Toward Efficient Deployment on 32-bit Embedded Devices
1. Introduction The emergence of quantum computing poses a significant threat to current public-key cryptosystems. Existing cryptographic schemes based on hard computational problems, such as integer factorization and discrete logarithms, are vulnerable to quantum algorithms, which can solve such problems in polynomial time [1,2,3]. In response to this looming threat, the field of post-quantum cryptography (PQC) has gained considerable attention from researchers and cryptographers alike.
Micro-Nano Dual-Scale Coatings Prepared by Suspension Precursor Plasma Spraying for Resisting Molten Silicate Deposit
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Impact of transforming karst mountainous forests into urban parks on plant diversity patterns
1 INTRODUCTION Karst terrain, shaped by the interaction of rainfall and groundwater with carbonate bedrock such as limestone and dolomite, comprises a unique landscape noted for its ecological significance (Zhang et al., 2010). These landscapes are vital hotspots for biodiversity conservation, characterized by specialized habitats, diverse vegetation, and rich biodiversity (Du et al., 2017; Zhang et al., 2010).
Coatings | Free Full-Text | Investigation on the Thermal-Mechanical Properties of YbRESiO5 (RE = Yb, Eu, Gd, Ho, Tm, Lu, Y, Sc): First-Principles Calculations and Thermal Performance Experiments
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
CMAS Corrosion Resistance of Plasma-Sprayed YSZ and Yb2O3-Y2O3-Co-Stabilized ZrO2 Coatings under 39-40 KW Spraying Power
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
A conserved N-terminal motif of CUL3 contributes to assembly and E3 ligase activity of CRL3KLHL22 - Nature Communications
Abstract The CUL3-RING E3 ubiquitin ligases (CRL3s) play an essential role in response to extracellular nutrition and stress stimuli. The ubiquitin ligase function of CRL3s is activated through dimerization. However, how and why such a dimeric assembly is required for its ligase activity remains elusive.
Efficient Implementations of Square-root Vélu's Formulas
Paper 2024/584 , Sun Yat-sen University , Fudan University , Sun Yat-sen University , Sun Yat-sen University Abstract In the implementation of isogeny-based cryptographic schemes, Vélu’s formulas are essential for constructing and evaluating odd degree isogenies. Bernstein et al. proposed an approach known as √élu, which computes an 𝓁-isogeny at a cost of̃ (√𝓁) finite field operations.
Influence of Spray Angle on Particle Deposition and Thermal Shock Lifetime of Embedded Micro-Agglomerated Particle Coatings
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
An ultramicroporous multi-walled metal-organic framework for efficient C2H2/CO2 separation under humid conditions
An ultramicroporous multi-walled metal–organic framework for efficient C2H2/CO2 separation under humid conditions The removal of carbon dioxide (CO2) from acetylene (C2H2) is not only industrially important for acetylene purification but also scientifically challenging owing to their high similarities in physical properties and molecular sizes.
Internal Diameter Atmospheric-Plasma-Sprayed High-Performance YSZ-Based Thermal Barrier Coatings
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A conserved N-terminal motif of CUL3 mediates assembly and licenses E3 ligase activation of CRL3KLHL22
Abstract The CUL3-RING E3 ubiquitin ligases (CRL3s) play an essential role in response to extracellular nutrition and stress stimuli. The ubiquitin ligase function of CRL3s is activated through E3-E3 dimerization. However, how and why such a dimeric assembly is required for its ligase activity remains elusive.
Effect of High-Temperature Thermal Shock on Solar Absorption Rate of Alumina Coating
1. Introduction With the rapid development of the aerospace industry, people are no longer limited to observing the Sun from afar, and closer observation has become a human demand. However, a closer exploration means that the detector will have to withstand higher temperatures. The U.S. Parker Solar Probe is the first aircraft to fly into the solar corona [1].
Damage Grading Evaluation of Thermal Barrier Coatings under CMAS Corrosion
1. Introduction Thermal barrier coating (TBCs) has been widely used in high-temperature components of ground gas turbines and aero engines. As one of the essential core technologies of aero-engine turbine blades, TBCS are used to block the direct contact between metal components and high-temperature gas. Its excellent thermal insulation performance can isolate metal components from hot gas and effectively protect substrate materials.
Quantifying Environmental Flow in the Form of Pulse Flow for Fish Protection
Abstract : Pulse flow, which includes base flow, peak flow, flow duration, occurrence time, and frequency, is a manifestation of environmental flow in rivers. This paper describes a methodological framework for determining pulse flow based on an analysis of fish spawning behavior and presents its application to the second Songhua River in northeastern China. Peak flow was determined based on the hydrographic-habitat relationship for fish spawning in conjunction with physical habitat simulation.
A Faster Software Implementation of SQISign
Paper 2023/753 A Faster Software Implementation of SQISign , School of Mathematics, Sun Yat-sen University, Guangzhou, China , School of Mathematics, Sun Yat-sen University, Guangzhou, China , Yanqi Lake Beijing Institute of Mathematical Sciences and Applications, Beijing, China, Yau Mathematical Sciences Center, Tsinghua University, Beijing, China , School of Mathematics, Sun Yat-sen University, Guangzhou, China, Guangdong Key Laboratory of Information Security, Guangzhou, China Abstract...
Discriminatory Gate‐Opening Effect in a Flexible Metal-Organic Framework for Inverse CO2/C2H2 Separation
Abstract Considering the significant application of acetylene (C2H2) in the manufacturing and petrochemical industries, the selective capture of impurity carbon dioxide (CO2) is a crucial task and an enduring challenge. Here, a flexible metal–organic framework (Zn-DPNA) accompanied by a conformation change of the Me2NH2+ ions in the framework is reported. The solvate-free framework provides a stepped adsorption isotherm and large hysteresis for C2H2, but type-I adsorption for CO2.
Public-key Compression in M-SIDH
Paper 2023/136 Public-key Compression in M-SIDH , Sun Yat-sen University , Sun Yat-sen University , Sun Yat-sen University , Sun Yat-sen University , Sun Yat-sen University Abstract Recently, SIKE was broken by the Castryck-Decru attack in polynomial time. To avoid this attack, Fouotsa proposed a SIDH-like scheme called M-SIDH, which hides the information of auxiliary points. The countermeasure also leads to huge parameter sizes, and correspondingly the public key size is relatively large.
Simulation of 1500 °C Thermal Shock for Novel Structural Thermal/Environmental Barrier Coatings System
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Dative B←N bonds based crystalline organic framework with permanent porosity for acetylene storage and separation
Dative B←N bonds based crystalline organic framework with permanent porosity for acetylene storage and separation† Weize Wang,‡a Linxia Wang,‡a Fei Du,a Gang-Ding Wang,b Lei Hou, *b Zhonghua Zhu, c Bo Liu *a and Yao-Yu Wangb Abstract The utilization of dative B←N bonds for the creation of crystalline organic framework (BNOF) has increasingly received intensive interest; however, the shortage of permanent porosity is an obstacle that must be overcome to guarantee their application as porous...
Dative B←N bonds based crystalline organic framework with permanent porosity for acetylene storage and separation
Dative B←N bonds based crystalline organic framework with permanent porosity for acetylene storage and separation Weize Wang, Linxia Wang, Fei Du, Gang-Ding Wang, Lei Hou, Zhonghua Zhu, Bo Liu and Yao-Yu Wang Abstract The utilization of dative B←N bonds for the creation of crystalline organic framework (BNOF) are receiving an increasingly intensive interest, while the short of permanent porosity is an obstacle that must be overcome to guarantee their applications as porous materials.
Effect of Doping Content of MgO on Solar Absorptivity to IR Emissivity Ratio of Al2O3 Coatings
Open AccessArticle by Han Zhu 1,2, Weize Wang 1,*, Dongdong Ye 3, Ting Yang 1, Dongpeng Li 1, Min Yang 1, Baohan Yuan 1 and Yihao Wang 1 1 Key Laboratory of Pressure System and Safety, Ministry of Education, School of Mechanical and Power Engineering, East China University of Science and Technology, No. 130 Meilong Road, Shanghai 200237, China 2 China Coal Xinji Lixin Power Generation Co., Ltd., Bozhou 236000, China 3 School of Artificial Intelligence, Anhui Polytechnic University, Wuhu...
An Alternative Approach for Computing Discrete Logarithms in Compressed SIDH
Paper 2021/1528 An Alternative Approach for Computing Discrete Logarithms in Compressed SIDH Abstract Currently, public-key compression of supersingular isogeny Diffie-Hellman (SIDH) and its variant, supersingular isogeny key encapsulation (SIKE) involve pairing computation and discrete logarithm computation. Both of them require large storage for precomputation to accelerate the performance.
Indium metal-organic frameworks based on pyridylcarboxylate ligands and their potential applications
Indium metal-organic frameworks based on pyridylcarboxylate ligands and their potential applications Indium metal-organic frameworks (In-MOFs) based on pyridylcarboxylate ligands represent a subclass of MOFs featuring diversity structures, high stability, and various properties. This review discusses the different aspects of In-MOFs including design, synthesis and structures, and typical potential applications in adsorption and separation, catalysis, and chemical sensor.
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