William Carroll on Muck Rack

William Carroll

Verified
Wabash
As seen in: Wabash Plain Dealer, Nature, PLOS ONE, JAMA (The Journal of the American Medical Association), Cell Press, The Lancet, Vancouver Sun, The Times (Frankfort), Chronicle-Tribune, The Indiana Plain Dealer, Peru Tribune and
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Articles

Detection of MEN1 resistance mutations in cell-free DNA from acute leukemia patients treated with menin inhibitors

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By Neerav Shukla, Karmelina Charalambous, Shanita Li, Kaitlyn H. Ko, Ruchi Patel, Mark D. Ewalt, Maria Luisa Sulis, William Carroll Verified, Maria E. Arcila, Neeman Mohibullah, Michael Berger, Ross Levine, Eytan M. Stein, Ronak Shah, Sheng Cai, Hilary Casanova, Eric Buehler, Cassidy Cobbs, Angela Rose Brannon
| Nature Verified
Dear Editor, Menin inhibitors have emerged as a targeted therapeutic strategy for patients with acute leukemias driven by KMT2A gene rearrangements (KMT2Ar) and NPM1 mutations, where aberrant menin-KMT2A interactions sustain HOX-MEIS1-dependent transcriptional programs that are critical for leukemogenesis [1,2,3,4]. Positive early-phase studies led to regulatory approval of both revumenib and ziftomenib for these leukemia subtypes [5, 6].
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Repeated application of transcranial ultrasound maintains spatial and recognition memory in 5xFAD mice with reduction of amyloid-β burden

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By Seung-Schik Yoo, Anvita Reddy Verified, William Carroll Verified, Kanyapat Ploypradith
| PLOS ONE
Loading metrics Open Access Peer-reviewed Research Article Citation: Yoo S-S, Reddy A, Carroll W, Ploypradith K (2025) Repeated application of transcranial ultrasound maintains spatial and recognition memory in 5xFAD mice with reduction of amyloid-β burden. PLoS One 20(11): e0336114.
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Determinants of survival after first relapse of acute lymphoblastic leukemia: a Children’s Oncology Group study - Leukemia

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By Susan R. Rheingold, Deepa Bhojwani, Xinxin Xu, Meenakshi Devidas, Brent L. Wood, Patrick Brown, Leonard A. Mattano, Stuart Winter Verified, Naomi J. Winick, William Carroll Verified, Elizabeth A. Raetz
| Nature Verified
Abstract Limited prognostic factors have been associated with overall survival (OS) post-relapse in childhood Acute Lymphoblastic Leukemia (ALL). Patients enrolled on 12 Children’s Oncology Group frontline ALL trials (1996–2014) were analyzed to assess for additional prognostic factors associated with OS post-relapse. Among 16,115 patients, 2053 (12.7%) relapsed. Relapse rates were similar for B-ALL (12.5%) and T-ALL (11.2%) while higher for infants (34.2%).
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