Wissam Mansour

Nayla Ahmed, MBBS OSA is increasingly recognized as a heterogeneous syndrome driven by distinct underlying pathophysiologic mechanisms known as endotypes.

Sleep Strategies Publish date: November 17, 2021 Obstructive sleep apnea (OSA) is characterized by repetitive upper airway collapse resulting in intermittent hypoxemia and hypercapnia, large intrathoracic pressure swings, and cortical arousals. The rate of apneas and hypopneas observed during sleep, the apnea-hypopnea index (AHI), has been used for decades to diagnose OSA and to classify its severity.

Publication HistoryPublished: March 16, 2017Accepted: February 23, 2017; Received in revised form: December 29, 2016; Received: May 9, 2016;