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Xiao-Ping Chen on Muck Rack

Xiao-Ping Chen

China
As seen in: Allergy - European Journal of Allergy and Clinical Immunology, Color Research & Application, Nature, Wiley Online Library, The Conversation, Canadian Journal of Infectious Diseases & Medical Microbiology, Roanoke Times, Bryan-College Station Eagle, Grand Island Independent, Yakima Herald-Republic and
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Articles

Post-translational modifications in metabolic reprogramming: implications for metabolic therapy and immunotherapy in cancer

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By Si-Jie Chen, Shi-Wei Yue, Hui-fang Liang, Xiao-Ping Chen, Bi-xiang Zhang, Wei Zhang, Yun-Pu Zhang, Hai-Xin Wu
| Nature Verified
Abstract Cancer metabolism is characterized by profound reprogramming, yet the mechanisms enabling rapid and precise adaptation remain incompletely understood. This review establishes post-translational modifications (PTMs) as the central processing unit of oncogenic metabolic reprogramming. PTMs execute a conserved three-tiered regulatory logic: they interpret oncogenic and environmental signals, command metabolic flux, and cement malignant phenotypes through epigenetic and feedback mechanisms.
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Regulation of lipoprotein processing by GPNMB in foamy macrophages: potential therapeutic targets for atherosclerosis - Nature Communications

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By Xiao-Ping Chen
| Nature Verified
Abstract The formation of foamy macrophages is often considered a pathological hallmark of atherosclerosis, but the underlying mechanisms remain elusive. Herein, we demonstrated that the transcription factor TFEC could upregulate the expression of Glycoprotein non-metastatic melanoma protein B (GPNMB) in atherosclerotic plaque foamy macrophages. Circulating levels of soluble GPNMB correlated positively with atherosclerotic severity.
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Middle power plays: How and when Mach middle managers use downward abuse and upward guanxi to gain and maintain power

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By Fong Keng-Highberger, Zhiyu Feng, Xiao-Ping Chen, Hu Li
| Wiley Online Library Verified
CONFLICT OF INTEREST STATEMENT There is no conflict of interest. REFERENCES , & (1991). Multiple regression: Testing and interpreting interactions. Sage. , & (2020). Abusive according to whom? Manager and subordinate perceptions of abusive supervision and supervisors' performance. Journal of Organizational Behavior, 41(8), 737–756. https://doi.org/10.1002/job.2472 , & (2002). The experience of power: Examining the effects of power on approach and inhibition tendencies.
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