Xiaohui Yang
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Articles by Xiaohui Yang
CRISPR knockout screen identifies MYD88/IRAK4 signaling as a mediator of deoxynivalenol-induced oxidative damage
Abstract Deoxynivalenol (DON) is a prevalent mycotoxin that poses serious risks to food and feed safety, particularly affecting pigs. However, the primary host factors mediating DON cytotoxicity remain poorly understood. Here, we perform a genome-wide CRISPR knockout (KO) screen in porcine intestinal epithelial IPI-2I cells and identify MYD88 and IRAK4 as the top-ranked genes conferring resilience to DON-induced cell death.
Contralateral tension pneumothorax after extubation following thoracoscopic wedge resection: a case report
Abstract Contralateral tension pneumothorax is a rare but potentially life-threatening complication after thoracic surgery and may be difficult to distinguish from more common postoperative respiratory complications. We report a case of a 53-year-old female patient who developed a right tension pneumothorax during recovery from anesthesia following a thoracoscopic left wedge resection performed under one-lung ventilation.
Probing Anharmonic Lattice Dynamics and Thermal Transport in Layered Perovskite Anode
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ATHENA promotes the assembly of the ATP synthase-associated macromolecular complex and cancer progression
Abstract The ATP synthase-associated macromolecular complex plays a crucial role in cellular energy homeostasis. However, the regulation and potential function of this complex remain poorly understood in cancer. Here, we identify a 170-amino acid protein encoded by the lncRNA LINC00528, which we term ATP synthase-associated macromolecular complex enhancing microprotein (ATHENA).
Microglial P2ry12 in the Basolateral Amygdala Underlies Neuropathic Pain-Induced Anxiety
1 Introduction Anxiety is the most prevalent negative emotional symptom associated with neuropathic pain (Hasenbring et al. 2014). The amygdala, primarily composed of the central amygdala (CeA) and BLA, is a core region involved in both chronic pain and anxiety (Inman et al. 2023; Li, Li, et al. 2025; Xue et al. 2025).
Three-dimensional aperture-driven photoacoustic tomography (3D-ADPAT)
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract As a powerful modality for biomedical research, photoacoustic computed tomography (PACT) offers the combination of optical specificity and acoustic penetration for in vivo visualization.
Orbital Degeneracy–Driven Spin Regulation Enables Multi-Electron Biomass Electrooxidation
, , , et al. “Orbital Degeneracy–Driven Spin Regulation Enables Multi-Electron Biomass Electrooxidation.” Advanced Functional Materials (2026): e76599. https://doi.org/10.1002/adfm.76599 Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request.
Dipole Moment Induced Micro-Nanopore Modulation Enables Dual-Functional Conductive Anion Exchange Composite Membranes
, , , et al. “Dipole Moment Induced Micro-Nanopore Modulation Enables Dual-Functional Conductive Anion Exchange Composite Membranes.” Advanced Functional Materials (2026): e76467. https://doi.org/10.1002/adfm.76467 Conflicts of Interest The authors declare no conflict of interest. Data Availability Statement The data that supports the findings of this study are available in the supplementary material of this article.
Training squared-hinge support vector machines by an explicit QUBO–Ising construction with quantum-annealing execution
Abstract Quantum annealers natively minimize quadratic unconstrained binary optimization (QUBO) problems, yet faithfully compiling continuous convex objectives into discrete binary forms with formal guarantees remains challenging. We present a complete, algebraically verifiable pipeline for training a linear squared-hinge support vector machine on quantum annealing hardware.
TRIM29 knockout pigs exhibit enhanced broad-spectrum disease resilience by amplifying type I interferon antiviral defenses
Loading metrics Open Access Peer-reviewed Research Article ? This is an uncorrected proof. Citation: Yang X, Zhong H, Cheng J, Jiang H, Tan J, Wang C, et al. (2026) TRIM29 knockout pigs exhibit enhanced broad-spectrum disease resilience by amplifying type I interferon antiviral defenses. PLoS Pathog 22(3): e1014023.
High‐Pressure Homogenization Modifies the Structure of Pediococcus acidilactici S1 Exopolysaccharide and Enhances Its Bile Salts Binding Capacity
Conflicts of Interest The authors declare no conflicts of interest. The final version of this manuscript was approved by all authors prior to publication. References , , , , and . 2023. “Optimization and Cholesterol-Lowering Activity of Exopolysaccharide From Lactiplantibacillus paraplantarum NCCP 962.” Applied Microbiology and Biotechnology 107, no. 4: 1189–1204. https://doi.org/10.1007/s00253-023-12372-z. , , , , , and . 2018.
Disitamab vedotin combined with anti-PD-1 antibody in a patient with SMARCA4-mutated gastric cancer: a case report
Abstract Background: SMARCA4-mutated gastric cancer is an extremely rare upper gastrointestinal malignancy characterized by high aggressiveness, early metastatic spread, poor response to chemo-radiotherapy, and dismal prognosis. Case presentation: Here, we report a case of SMARCA4-mutated undifferentiated gastric carcinoma. The patient was initially diagnosed by gastroscopy and pathological examination, followed by radical gastrectomy.
Establishment of a Point‐of‐Care Testing Method for Rapid Detection of Multiple Respiratory Virus Antigens Based on a Dual‐Drive Microfluidic Chip
Conflicts of Interest Josh Zixi Lee was employed by the company Beijing MicVic Biotech Co. Ltd. The other authors declare no conflicts of interest. Data Availability Statement Data will be made available on request. Supporting Information Filename Description jmv70811-sup-0001-Supplementary_material_final_version.docx4 MB Supplementary Figure 1: Schematic diagram of different models in the labeling region and reference region.
Development and validation of a neutrophil percentage-to-albumin ratio
Back to Journals » Journal of Inflammation Research » Volume 19 Original Research Onco-inflammation Authors Yang X, Huang L, Qu S Received 26 September 2025 Accepted for publication 26 January 2026 Published 5 February 2026 Volume 2026:19 Pages 1—20 DOI https://doi.org/10.2147/JIR.S566289 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Subhasis Chattopadhyay Xiaohui Yang,1 Lu Huang,2 Song Qu1 1Department of...
The NMDAR/TRPM4 death complex is a major promoter of disease progression in the 5xFAD mouse model of Alzheimer’s disease - Molecular Psychiatry
Abstract Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder, characterized by cognitive decline and neuronal degeneration. The formation of amyloid β plaques and neurofibrillary tangles are key morphological features of AD pathology. However, the specific molecules responsible for the cell destruction triggered by amyloid β and tau proteinopathies in AD has not yet been identified.
AMCIU: An Adaptive Multimodal Complementary Intent Understanding Method
Abstract With the aging of society, assistive companion robots have become an important solution to address the daily needs of the elderly. However, the elderly may suffer from slow thinking and memory loss, which makes it difficult for robots to accurately capture executable intentions during human-robot interaction. To address this challenge, this paper proposes an Adaptive Multimodal Complementary Intent Understanding Approach (AMCIU).
Decoding the Influence of Monomer Structures on the Electrical Double-Layer of Alkaline Fuel Cells
Decoding the Influence of Monomer Structures on the Electrical Double-Layer of Alkaline Fuel Cells Alkaline polymer electrolytes (APEs) are extensively used in fuel cells and electrolysers due to their safety and low-cost advantages. Recently, scientists have been exploring their potential as electrochemical reaction catalysts, allowing APEs to function as ion transport channels and actively participate in catalytic reactions, exhibiting a bifunctional characteristic.
Full article: The effects of music therapy on pain and anxiety in young nulliparous patients undergoing laparoscopic cystectomy for endometriosis: a randomized controlled trial
Abstract Background Endometriosis (EMS) is associated with a markedly increased incidence of depression and anxiety, primarily due to cyclic pain, concerns about infertility from impaired ovarian function, and fear of disease recurrence. Surgery and its associated pain may trigger both emotional and physiological stress responses.
Trends in HPV-positive cervical cancer prevalence: a retrospective study from 2013 to 2020 - Virology Journal
References Arbyn M, Weiderpass E, Bruni L, de Sanjose S, Saraiya M, Ferlay J, Bray F. Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. Lancet Glob Health. 2020;8(2):e191–203. Article PubMed Google Scholar Cohen PA, Jhingran A, Oaknin A, Denny L. Cervical cancer. Lancet. 2019;393(10167):169– 182. Article PubMed Google Scholar Chua BWB, Ma VY, Alcantar-Fernandez J, Wee HL. Is it time to genotype beyond HPV16 and HPV18 for cervical Cancer screening?? Int J Public Health.
Tailoring Interfaces and Networks in Functionalized Graphene‐Carbon Fiber Reinforced Polyamide Composites for Enhanced Thermal and Mechanical Properties
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description pc30138-sup-0001-Supinfo.docxWord 2007 document , 1.9 MB Table S1. The addition weight ratio of each component in the ISP-PFG composites. Figure S1. TGA curves of GNP, FG, and ISP-FG masterbatch. Figure S2. (a, b) Cross-section of SEM images of ISP-PG composites. Figure S3. XRD pattern of PA6 matrix. Figure S4. (a, b) Topography of 3D image and floor plan of PA6 matrix.
Graphene/C-PDA/Carbon Fiber Ternary Heterostructure Network Enables Lightweight Polyimide Composites with Enhanced Electromagnetic Shielding and Thermal Management Capabilities
Graphene/C-PDA/Carbon Fiber Ternary Heterostructure Network Enables Lightweight Polyimide Composites with Enhanced Electromagnetic Shielding and Thermal Management Capabilities High-performance polymer composites (HFPCs) integrating electromagnetic interference (EMI) shielding and thermal conductivity (TC) are urgently needed for advanced electronics, However, challenges remain in achieving a balanced integration of TC, thermally stable, conductivity, and EMI shielding within a single material.
Impact of Institutional Coordination on Analyst Decisions During Hedge Fund Activism
DOI: https://doi.org/10.33423/jabe.v27i3.7642 Keywords: business, economics, institutional coordination, analyst recommendations, hedge fund activism References Ben-David, I., Franzoni, F., & Moussawi, R. (2012). Hedge fund stock trading in the financial crisis of 2007–2009. The Review of Financial Studies, 25(1), 1–54.
The crucial roles of platelets as immune mediators in sepsis
Back to Journals » Journal of Inflammation Research » Volume 18 Authors Yang X, Song J, Ma H, Hua N, Bai Y, Ju Y, Shen JW, Zheng W, Jiang S Received 15 May 2025 Accepted for publication 9 August 2025 Published 16 September 2025 Volume 2025:18 Pages 12825—12845 DOI https://doi.org/10.2147/JIR.S535701 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Anh Ngo Xiaohui Yang,1,2 Jiasheng Song,1,2 Hui Ma,2 Ning Hua,2 Yanan...
Improved-third-order-extended-state-observer-based sliding-mode control using singular perturbation theory for flexible-joint robot
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Effect of braiding architecture on the tensile properties and damage mechanisms of 3D braided composites
Supporting Information Filename Description pc29808-sup-0001-Supinfo.docxWord 2007 document , 753.6 KB Data S1. Supporting Information. REFERENCES 1, , , , , . Compressive anisotropy effects and crack evolution mechanisms of 3D5d braided composites induced by thermo-oxidative ageing. Compos Sci Technol. 2023; 240:110102. doi:10.1016/j.compscitech.2023.110102 2, , , , , .
Insight into the Orbital Origins of Anisotropic Carrier Mobility in TaS2X2 (X=Cl, Br, I) Monolayer with Highly Efficient Photocatalytic Hydrogen Evolution
Insight into the Orbital Origins of Anisotropic Carrier Mobility in TaS2X2 (X=Cl, Br, I) Monolayer with Highly Efficient Photocatalytic Hydrogen Evolution Discovering and designing novel narrow-band gap semiconductor materials with efficient charge carrier mobility is a critical strategy to address the energy crisis. However, the progress in developing high-performance photocatalysts has been hindered due to an unclear understanding of the structure-property relationship.
The Elasto-Plastic Contact Models of Cylinder-Based and Sphere-Based Fractal Rough Surfaces
1. Introduction For many engineering applications, knowledge about contact between surfaces is of fundamental importance to understand friction, wear, lubrication, friction-induced vibrations and noise, thermal and electrical contact resistance, etc. At the microscopic level, surfaces that include different asperities are rough. The contact between rough surfaces is characterized by the interaction of asperities.
Does Information Asymmetry Affect Firm Disclosure? Evidence from Mergers and Acquisitions of Financial Institutions
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Capacitance-Voltage Studies on Electrostatically Actuated MEMS Micromirror Arrays
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My IRA: Making Up Ground or Cashing It in?
DOI: https://doi.org/10.33423/jabe.v27i1.7504 Keywords: business, economics, IRA management, life cycle savings, capital gains and savings References Barsky, R.B., Juster, F.T., Kimball, M.S., & Shapiro, M.D. (1997).
HDAC6 Facilitates PRV and VSV Infection by Inhibiting Type I Interferon Production
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Catalytic oxidative depolymerization of lignin dimers over NiMn-MOF-derived catalysts in the presence of oxygen
Catalytic oxidative depolymerization of lignin dimers over NiMn-MOF-derived catalysts in the presence of oxygen† The catalytic oxidative depolymerization of lignin and its dimers is key for the effective utilization of biomass. In this work, a metal–organic framework (MOF) was chosen as the precursor, and a series of nickel–manganese bimetallic catalysts with different metal ratios were prepared via a hydrothermal method using 1,3,5-tricarboxylic acid as the ligand.
Dynamic changes of lung sRAGE in mice with chronic obstructive pulmonary disease induced by cigarette smoke exposure
Citation: He Y, Liang H, Yang X, Hao F, Huang K, Wang Q (2024) Dynamic changes of lung sRAGE in mice with chronic obstructive pulmonary disease induced by cigarette smoke exposure. PLoS ONE 19(11): e0313872. https://doi.org/10.1371/journal.pone.0313872 Editor: Misbahuddin Rafeeq, King Abdulaziz University Faculty of Medicine, SAUDI ARABIA Received: May 20, 2024; Accepted: November 1, 2024; Published: November 26, 2024 Copyright: © 2024 He et al.
Preparation of a nitrogen and phosphorus containing lignin-based flame retardant using oxidized kraft lignin and its application in phenolic foam
Preparation of a nitrogen and phosphorus containing lignin-based flame retardant using oxidized kraft lignin and its application in phenolic foam In order to improve the flame retardancy of phenolic foam (PF), it is a feasible method to add flame retardants. Due to the similar structure of lignin to phenol, this provides the possibility of developing lignin-based flame retardants to partially replace phenol.
A Fault Diagnosis Method for Pumped Storage Unit Stator Based on Improved STFT-SVDD Hybrid Algorithm
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Relationship between surfactant content and the properties of microfibrillated cellulose/high density polyethylene composites
REFERENCES 1, , , , . Development of biopolymer composite films based on chicory extract reinforced polyvinyl alcohol/chitosan blend via green approach for flexible optoelectrical devices. J Appl Polym Sci. 2024; 141(13):e55154. 2, . Development of high-performance biopolymer nanocomposites derived from carboxymethyl chitosan/boehmite via green synthesis. Polym Compos. 2023; 44(2): 1135-1148. 3, , , , , .
Permeability Characteristics of Improved Loess and Prediction Method for Permeability Coefficient
1. Introduction Loess, a material extensively employed in engineering applications, finds wide usage in various projects such as the construction of cement–soil waterproof curtains, artificial water-impermeable layers, and landfills. Among the crucial engineering properties of loess, permeability holds particular significance, directly influencing the practical implementation of engineering projects [1].
Integrated UAV and Satellite Multi-Spectral for Agricultural Drought Monitoring of Winter Wheat in the Seedling Stage
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Enhanced energy efficiency of aqueous organic redox flow batteries: Carbon-based heterostructure electrodes guided by interface engineering strategy
Enhanced energy efficiency of aqueous organic redox flow batteries: Carbon-based heterostructure electrodes guided by interface engineering strategy As an emerging large-scale energy storage technology, aqueous organic redox flow batteries (AORFBs) have drawn widespread focus in the field of energy research.
Casimir Effect in MEMS: Materials, Geometries, and Metrologies-A Review
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Pharmaceuticals | Free Full-Text | Iron−Based Metal-Organic Frameworks as Multiple Cascade Synergistic Therapeutic Effect Nano−Drug Delivery Systems for Effective Tumor Elimination
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Preparation of a reactive flame retardant by functional modification of lignin and its application in phenolic foam
Preparation of a reactive flame retardant by functional modification of lignin and its application in phenolic foam With the emergence of new standards for fire prevention, phenolic foam has attracted increasing attention due to its satisfactory cleanliness and flame retardancy. With the increasing exhaustion of fossil energy and environmental problems, finding renewable energy sources to replace petroleum-derived phenol has become a new research hotspot.
A Highly Sensitive Dual-Drive Microfluidic Device for Multiplexed Detection of Respiratory Virus Antigens
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Superconducting diode effect and interference patterns in kagome CsV3Sb5 - Nature
Abstract The interplay among frustrated lattice geometry, non-trivial band topology and correlation yields rich quantum states of matter in kagome systems1,2. A series of recent members in this family, AV3Sb5 (A = K, Rb or Cs), exhibit a cascade of symmetry-breaking transitions3, involving the 3Q chiral charge ordering4,5,6,7,8, electronic nematicity9,10, roton pair density wave11 and superconductivity12. The nature of the superconducting order is yet to be resolved.
Effect of Facet on Local Electron Density of Oxygen Vacancy in Catalysts for Nitrogen Electro‐Reduction
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202312210-sup-0001-SuppMat.pdf3.2 MB Supporting Information References 1, , , , , , , , , Angew. Chem. Int. Ed. 2022, 61, 202203022. 2, , Small 2020, 16, e2002885. 3, , , , , , Adv. Mater. 2021, 33, 2007650. 4, , , , , Adv. Funct. Mater. 2021, 31, 2101872. 5, , , , , , , , , , , Angew. Chem. Int. Ed. 2021, 60, 5257. 6, , , , , , , , , Energy Environ. Sci. 2017, 10, 2516. 7, Nat. Catal. 2019, 2, 377.
HAR-Net: An Hourglass Attention ResNet Network for Dangerous Driving Behavior Detection
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Comparative Transcriptome Analysis of High- and Low-Growth Genotypes of Eucalyptus urophylla in Response to Long-Term Nitrogen Deficiency
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Service Characteristic Evolution of 3D Four‐Directional Braided C/SiC Ceramic Matrix Composites Under Space Electron Radiation Erosion Environment
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adem202301489-sup-0001-SuppData-S1.pdf695 KB Supplementary Material References 1 , , , , , , , , , , , Adv. Ceram. 2017, 38, 311. 2 , , , , , , , , Corros. Sci. 2019, 147, 212. 3 , , , , , Prog. Aerosp. Sci. 1985, 56, 307. 4 , Nat. Mater. 2018, 17, 846. 5 , , , , , , Adv. Mater. 2019, 31, 1807738. 6 , , , , , J. Inorg. Mater. 2022, 38, 561. 7 , , , , , , , , , Int. J. Appl. Ceram. Technol. 2022, 19, 1956.
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