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Articles by Xiaoling Hu
Age-stratified clinical characteristics of hand, foot, and mouth disease in children and its guiding value for diagnosis and treatment
Abstract Objective: To investigate the age-stratified differences in core clinical characteristics of children with hand, foot and mouth disease (HFMD) and their clinical reference value for clinical diagnosis and treatment. Methods: This single-center retrospective study enrolled 216 hospitalized children with HFMD from January 2022 to December 2024. Patients were stratified into four age groups: ≤1 month, 1 month–1 year, 1–3 years, and >3 years.
On-demand formation of ultrathin liquid metal hydrogel tattoos for conformal and low-impedance bioelectronics
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Ultrathin conductive hydrogels provide conformal and stable contact for flexible bioelectronics, which is critical for achieving the low impedance necessary for high-quality electrophysiological signal acquisition.
Preliminary evidence for enhanced auditory cortex activation and mental development after gene therapy in children with autosomal recessive deafness 9 | Nature Human Behaviour
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Abstract Individuals with congenital deafness that have received gene therapy represent a unique group who experience hearing recovery and speech development. However, it is unclear how hearing-related cortex changes because of gene therapy. Here we study neural processing in ten patients using functional near-infrared spectroscopy and electroencephalography during a six-month follow-up period.
By Jiajia Zhang, Chunchun Hu, Yuxin Chen, Sha Yu Verified, Xiaoling Hu, Lin Chen, Shan Sun, fei chen, Zengzhi Guo, Xinyang Weng, Yang-wenyi Liu
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Nature
Verified
Constitutive Model for Thermal-Oxygen-Aged EPDM Rubber Based on the Arrhenius Law
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Fenamates: Forgotten treasure for cancer treatment and prevention: Mechanisms of action, structural modification, and bright future
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. REFERENCES 1, , . Tumors: wounds that do not heal. N Engl J Med. 1986; 315(26): 1650-1659. 2. Inflammation and cancer. Environ Health Prev Med. 2018; 23(1): 50. 3, . Inflammation A driving force speeds cancer metastasis. Cell Cycle. 2009; 8(20): 3267-3273. 4, , , et al. Inflammation and tumor progression: signaling pathways and targeted intervention. Signal Transduct Target Ther. 2021; 6: 263. 5, .
Animal Pose Estimation Based on Contrastive Learning with Dynamic Conditional Prompts
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Front Cover: An embedded obstacle type micromixer‐concentration gradient generator based on capillary driven
Graphical Abstract DOI: 10.1002/elps.202300164 The front cover picture shows an embedded obstacle-type micromixer-concentration gradient generator that is capillary driven. The herringbone structure for mixing, and the palisade-shaped small channels at the outlet are part of the micro device design. Two solutions flow in from the two inlets, respectively, flow out from the outlet, and discharge the air in the device channel during capillary filling.
Submonomer synthesis of inverse polyamidoamine (i‐PAMAM) dendrimer antibacterials
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Long-term effects of mobile exoneuromusculoskeleton (ENMS)-assisted self-help telerehabilitation after stroke
Provisionally accepted Hong Kong Polytechnic University, Kowloon, Hong Kong, SAR China Queen Elizabeth Hospital (QEH), Kowloon, Hong Kong, SAR China Investigation on long-term effects of robot-assisted poststroke rehabilitation is challenging because of the difficulties in administration and follow-up of individuals throughout the process.
Reconfigurable Intelligent Surface-Enabled Integrated Sensing and Communication in 6G
2024 | Buch As the main trend and key enabling technology for next-generation wireless networks (i.e., 6G), integrated sensing and communication (ISAC) can effectively improve spectrum efficiency, hardware efficiency, and information processing efficiency. However, it faces several deficiencies, including limited coverage due to high-frequency signals and limited communication-sensing performance due to uncontrollable wireless environments.
Sonographic features of diffuse giant cell tumor of the tendon sheath in the shoulder: A case report
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest. Supporting Information Filename Description jcu23618-sup-0001-Video_1.wmvWindows Media video, 45.8 MB Video 1: B- mode sonographic feature of GCTTS in the shoulder. REFERENCES 1, , , et al. Tenosynovial giant cell tumor. Folia Med Cracov. 2022; 62(2): 93-107. 2, , , et al. Giant cell tumor of tendon sheath: open surgery or arthroscopic synovectomy? A systematic review of the literature. Orthop Traumatol Surg Res.
An embedded obstacle type micromixer‐concentration gradient generator based on capillary driven
CONFLICT OF INTEREST STATEMENT The authors have declared no conflict of interest. Supporting Information Filename Description elps7878-sup-0001-SuppMat.docx2.8 MB Supporting Information elps7878-sup-0002-videoS1.gif733.7 KB Supporting Information elps7878-sup-0003-videoS2.gif635.3 KB Supporting Information elps7878-sup-0004-videoS3.gif661.1 KB Supporting Information REFERENCES 1. Control and detection of chemical reactions in microfluidic systems. Nature. 2006; 442: 394–402. 2, , , , , , et al.
A Fast and Effective Spike Sorting Method Based on Multi-Frequency Composite Waveform Shapes
Abstract : Accurate spike sorting to the appropriate neuron is crucial for neural activity analysis. To improve spike sorting performance, it is essential to fully leverage each processing step, including filtering, spike detection, feature extraction, and clustering. However, compared to the latter two steps that were widely studied and optimized, the filtering process was largely neglected.
Somatic Calcium Signals from Layer II/III Motor Cortex for Continuous Neural Decoding
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Optimized Design and Preparation of Ag Nanoparticle Multilayer SERS Substrates with Excellent Sensing Performance
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A specific low-density neutrophil population correlates with hypercoagulation and disease severity in hospitalized COVID-19 patients
Research ArticleCOVID-19Immunology Open Access | 10.1172/jci.insight.148435 Samantha M. Morrissey,1,2 Anne E. Geller,1,2 Xiaoling Hu,2 David Tieri,3 Chuanlin Ding,2 Christopher K. Klaes,4 Elizabeth A. Cooke,5 Matthew R. Woeste,1,2 Zachary C. Martin,5 Oscar Chen,5 Sarah E. Bush,5 Huang-ge Zhang,1 Rodrigo Cavallazzi,6 Sean P. Clifford,5 James Chen,5 Smita Ghare,7 Shirish S. Barve,7 Lu Cai,8 Maiying Kong,9 Eric C. Rouchka,10 Kenneth R. McLeish,11 Silvia M. Uriarte,4 Corey T.
Evaluation of disease staging and chemotherapeutic response in non-small cell lung cancer from patient tumor-derived metabolomic data
Highlights • Designs workflow for personalized prediction of response to first-line chemotherapy. • Performs systematic metabolomic analysis of lung cancer fresh tumor core biopsies. • Machine learning analyses differentiate between treatment responses and disease stage. • Predicts response and identifies metabolites associated with patient classifications.
Neuro-perceptive discrimination on fabric tactile stimulation by Electroencephalographic (EEG) spectra
Loading metrics Open Access Peer-reviewed Research Article Jiao Jiao , Xiaoling Hu , Yanhuan Huang, Junyan Hu, Chihchia Hsing, Zhangqi Lai, Calvin Wong, John H. Xin Jiao Jiao, Xiaoling Hu, Yanhuan Huang, Junyan Hu, Chihchia Hsing, Zhangqi Lai, Calvin Wong, John H. Xin Published: October 28, 2020 https://doi.org/10.1371/journal.pone.0241378 Figures Abstract The precise evaluation of sensory perceptions during fabric-skin interactions is still poorly understood in neuroscience.
Considering gemcitabine‐based combination chemotherapy as a potential treatment for advanced esophageal cancer: a meta‐analysis of randomised trials
META‐ANALYSIS Jian Yang Translational Medicine Research Center, Shanxi Medical University, Taiyuan, Shanxi, PR China Department of Pathology &, Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical University, Taiyuan, PR China These authors contributed equally to this work Search for more papers by this author Xiao Liang Department of Pathology &, Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi...
Ternary Modular Molecular Co-Assembly with Flexibly Tailored Chiroptical Properties
Ternary Modular Molecular Co-Assembly with Flexibly Tailored Chiroptical Properties Rational design of chiroptical active materials from multi-component co-assembly remains great challenges ascribed to the spontaneous pathway competition and complexity.
Tumor Microenvironment following Gemcitabine Treatment Favors Differentiation of Immunosuppressive Ly6Chigh Myeloid Cells
Caijun Wu, Xiaobin Tan, Xiaoling Hu, Mingqian Zhou, Jun Yan and Chuanlin Ding J Immunol January 1, 2020, 204 (1) 212-223; DOI: https://doi.org/10.4049/jimmunol.1900930 Key Points Hyperexpression of GM-CSF in tumor cells promotes M-MDSC immunosuppression. Efferocytosis enhances immunosuppression of Ly6Chigh myeloid cells. Chemoresistance decreases the sensitivity to CTL-induced cytotoxicity.
Tumor Microenvironment following Gemcitabine Treatment Favors Differentiation of Immunosuppressive Ly6Chigh Myeloid Cells
Caijun Wu, Xiaobin Tan, Xiaoling Hu, Mingqian Zhou, Jun Yan and Chuanlin Ding J Immunol November 27, 2019, ji1900930; DOI: https://doi.org/10.4049/jimmunol.1900930 Key Points Hyperexpression of GM-CSF in tumor cells promotes M-MDSC immunosuppression. Efferocytosis enhances immunosuppression of Ly6Chigh myeloid cells. Chemoresistance decreases the sensitivity to CTL-induced cytotoxicity.
Tumor Microenvironment Modulates Immunological Outcomes of Myeloid Cells with mTORC1 Disruption
Chuanlin Ding, Xiaomin Sun, Caijun Wu, Xiaoling Hu, Huang-ge Zhang and Jun Yan J Immunol March 1, 2019, 202 (5) 1623-1634; DOI: https://doi.org/10.4049/jimmunol.1801112 Abstract The role of the mTOR signaling pathway in different myeloid cell subsets is poorly understood in the context of tumor development.
Tumor Microenvironment Modulates Immunological Outcomes of Myeloid Cells with mTORC1 Disruption
Chuanlin Ding, Xiaomin Sun, Caijun Wu, Xiaoling Hu, Huang-ge Zhang and Jun Yan J Immunol January 21, 2019, ji1801112; DOI: https://doi.org/10.4049/jimmunol.1801112 Abstract The role of the mTOR signaling pathway in different myeloid cell subsets is poorly understood in the context of tumor development.
Yeast-Derived Particulate β-Glucan Treatment Subverts the Suppression of Myeloid-Derived Suppressor Cells (MDSC) by Inducing Polymorphonuclear MDSC Apoptosis and Monocytic MDSC Differentiation to APC in Cancer | The Journal of Immunology
AbstractMyeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature myeloid cells that promote tumor progression. In this study, we demonstrated that activation of a C-type lectin receptor, dectin-1, in MDSC differentially modulates the function of different MDSC subsets.
STAT3 Signaling in B Cells Is Critical for Germinal Center Maintenance and Contributes to the Pathogenesis of Murine Models of Lupus
Ab maturation as well as memory B and plasma cell differentiation occur primarily in the germinal centers (GCs). Systemic lupus erythematosus (SLE) may develop as a result of enhanced GC activity. Previous studies have shown that the dysregulated STAT3 pathway is linked to lupus pathogenesis. However, the exact role of STAT3 in regulating SLE disease progression has not been fully understood.
Preparation of surface-imprinted microspheres with effectively controlled by orientated template immobilization using highly cross-linked raspberry-like microspheres for selective recognition of immunostimulating peptide - Journal of Materials Chemistry B
The surface–imprinted microspheres were controllably synthesized using ionic liquid–functionalized microspheres with highly cross–linked raspberry–like structure as matrix via surface molecular self–assembly and precipitation polymerization in aqueous media at room temperature. Immunostimulating hexapeptide of human (IHH) with medical properties was chosen as a template molecule in the preparation of different molecularly imprinted microspheres (MIMs).
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