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Xiaoying Shen

As seen in: Nature, PLOS, MDPI, Royal Society of Chemistry, BioRxiv, Cell Host & Microbe, Cell Reports, Canadian Journal of Infectious Diseases & Medical Microbiology, Dove Medical Press, Dialnet - Universidad de La Rioja and
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Articles

Unraveling the Mechanism of Cuochuangling pills in Rosacea Treatment: | CCID

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By Xiaoying Shen, Donghu Liu, Zhengjin Zhu
| Dove Medical Press
Back to Journals » Clinical, Cosmetic and Investigational Dermatology » Volume 19 Authors Shen X, Liu D, Zhu Z, Zhao S, Yan X, Li M Received 6 November 2025 Accepted for publication 17 February 2026 Published 4 March 2026 Volume 2026:19 579507 DOI https://doi.org/10.2147/CCID.S579507 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Prof.
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Germline-targeting HIV Envelope SOSIP immunization more frequently elicits broadly-neutralizing antibody precursor responses in infant compared to juvenile rhesus macaques

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By Xintao Hu, John J Isaac, Xiaoying Shen, Yasmine A Issah
| BioRxiv
Abstract A vaccine capable of inducing broadly neutralizing antibodies (bnAbs) is essential for effective prevention against HIV in children and adolescents. Germline-targeting vaccine strategies aim to stimulate bnAb precursor B cells through carefully designed immunogens, such as the stabilized SOSIP trimers, which mimic native HIV envelope (Env) proteins while presenting key neutralizing epitopes to germline B cell receptors.
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Convergence and divergence of B cell responses in two HIV-1 Env immunizations in Rhesus macaques - Communications Medicine

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By Maria Blasi, Taylor J. McGee, Xiaoying Shen, Melissa Kerkau, Andrea Cara, Kurt Wollenberg, Kevin Saunders, Mary Klotman, Guido Ferrari
| Nature Verified
Abstract Sequential multivalent immunizations are used to counter diversity in rapidly mutating viruses. Here, we evaluated the effect of HIV-1 immunogen formats on the binding profile of memory B-cells elicited in two independent Rhesus macaque trials. In one trial, female Rhesus macaques were immunized with a multiclade HIV-1 gp120 envelope glycoprotein (Env) cocktail and bled two weeks post final immunization.
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