A new AI capability that delivers analysis-ready Media Intelligence. More than just a product launch, this is a shift in how communications teams monitor, understand and act on media coverage.
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Get in touch with Xing
Contact Xing, search articles and posts on X, monitor coverage, and track replies from one place.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Abstract B cells are crucial for adaptive immunity, orchestrating humoral responses by producing antibodies essential for pathogen clearance. Here, we show that Poly(rC) binding protein 1 (Pcbp1), a multifunctional RNA binding protein, is a key regulator of antibody production in B cells.
We subsequently developed a dual AAV9 system where the adenine base editor (SpRY-HF1 ABE8e) was controlled by a cardiac-specific troponin T (cTnT) promoter74,75,76 and divided into two vectors using Npu intein77 (Figure 3A). To maximize cardiac targeting while minimizing off-target editing in other organs, we administered total 1.5×1012 genomic copies of AAV particles at a 1:1 ratio via intrathoracic injection (I.T.) to 6-week-old Tnni3R193H/R193H mice (Figure 3B).
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.