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Articles

Synthetic food pigment sunset yellow potentiates food allergy via immune dysregulation and intestinal barrier dysfunction

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By Dingjun Wei, Qiang Huang, xue feng, Philippe Madjirebaye, Yuting Fan, YiKe Huang, Xuli Wu, Mingchan Deng
| Nature Verified
Abstract Emerging evidence from clinical and experimental studies has suggested potential associations between artificial food pigments like Sunset Yellow (SY) and allergic reactions, though their mechanistic contributions remain unclear. This study investigated the immunological and epithelial effects of the synthetic pigment SY using a translational approach integrating mouse model assays.
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Analysis of risk factors for hypothyroidism in initially euthyroid patients with positive thyroid autoantibodies: a multicenter retrospective cohort study

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By xue feng, Xuan Lyu, Yating Gao, Xu Gao, Rui Gao
| Frontiers
Abstract Background: Thyroid autoantibody positivity is a common immune marker and a major precursor of hypothyroidism. Currently, there is a lack of effective tools and risk stratification criteria for identifying individuals at risk of its progression to either overt or subclinical hypothyroidism. Objective: To investigate the independent risk factors for future onset of hypothyroidism and determine an optimal anti-thyroid peroxidase antibody (TPOAb) cutoff for identifying high-risk individuals.
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A LASSO-based nomogram for predicting acute bilirubin encephalopathy in newborns with severe hyperbilirubinemia

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By Qifa Hu, Haixia Zhu, xue feng, Hongxing Li, Zhenzhu Yao
| Frontiers
Abstract Background: To develop and validate a nomogram for predicting acute bilirubin encephalopathy (ABE) in newborns with severe hyperbilirubinemia. Methods: A retrospective analysis was conducted on 287 newborns with severe hyperbilirubinemia who visited the neonatal department of Shenzhen Children's Hospital from January 2015 to December 2022.
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