Xueying Fan

Abstract The rapid growth of single-cell and spatial omics has outpaced computational methods capable of unifying these data into a cohesive framework for tissue atlas construction and cross-sample analysis. A critical bottleneck lies in the inability of existing tools to co-embed cells from diverse technologies-spanning transcriptomics, epigenomics, and proteomics-into a shared reference space while preserving spatial architecture and molecular specificity.

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1 Introduction Passive Radiative Cooling (PRC) is a spontaneous effect by which an object can dissipate its thermal energy to outer space through the atmospheric transparency windows (8–13 µm), possibly reaching a sub-ambient temperature.[1-3] This effect could not just help reduce our growing electricity needs for cooling but also help curb global warming and greenhouse gas emissions.