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Yafei Yin on Muck Rack

Yafei Yin

As seen in: Nature, Wiley Online Library, Royal Society of Chemistry, Cell Press
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Articles

Methodological concerns regarding the CAD EYE™ trial in FIT-positive screening colonoscopy

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By Qinghai Wang, Yafei Yin, Yinghui Shang
| Wiley Online Library Verified
No abstract is available for this article. DATA AVAILABILITY STATEMENT Data sharing is not applicable to this article as no datasets were generated or analysed during the current study. REFERENCES 1, , , , , , et al. Efficacy of an artificial intelligence system for lesion detection and characterization (CADe and CADx) during colonoscopy following positive faecal immunochemical test in a colorectal cancer screening programme: a randomized clinical trial. Colorectal Dis. 2026; 28:e70426.
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ZBP1 senses splicing aberration through Z-RNA to promote cell death

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By Zhang-Hua Yang, Puqi Wu, Bo-Xin Zhang, Jia Huang, Lei Wu, Yuenan Zhou, Yuanhui Mao, Yafei Yin, Xiurong Wu, Baizhou Li, Rongbin Zhou, Han-Ming Shen, Sheng Nie, Zhi-Yu Cai, Wei Mo, Cong-Rong Yang, Shuang-Hui Guo
| Cell Press Verified
Keywords spliceosome splicing aberration Z-RNA ZBP1 necroptosis Get full text access Log in, subscribe or purchase for full access. References 1. Wan, R. ∙ Bai, R. ∙ Zhan, X. ... How Is Precursor Messenger RNA Spliced by the Spliceosome? Annu. Rev. Biochem. 2020; 89:333-358 2. Wilkinson, M.E. ∙ Charenton, C. ∙ Nagai, K. RNA Splicing by the Spliceosome Annu. Rev. Biochem. 2020; 89:359-388 3. Lee, Y. ∙ Rio, D.C. Mechanisms and Regulation of Alternative Pre-mRNA Splicing Annu. Rev. Biochem. 2015; 84:291-323 4. Zhang, Y.
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Dynamic properties of transcriptional condensates modulate CRISPRa-mediated gene activation - Nature Communications

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By Tao Cheng, Shengbai Sun, Yafei Yin, Hongqing Liang, Nan Liu, Wei Zou
| Nature Verified
Abstract CRISPR activation (CRISPRa) is a powerful tool for endogenous gene activation, yet the mechanisms underlying its optimal transcriptional activation remain unclear. By monitoring real-time transcriptional bursts, we find that CRISPRa modulates both burst duration and amplitude. Our quantitative imaging reveals that CRISPR-SunTag activators, with three tandem VP64-p65-Rta (VPR), form liquid-like transcriptional condensates and exhibit high activation potency.
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