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Yi Yin

As seen in: Nature, Wiley Online Library, Memory Studies, Frontiers, IEEE, MDPI, Taylor & Francis Online, ACS Publications, JAMA: Journal of the American Medical Association, Science Magazine and
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Articles

First-generation monovalent vaccines blocked transmission of Delta and Omicron variants of SARS-CoV-2 in China

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By Tim K. Tsang, Mengmeng Ma, Can Wang, HONGYAN WANG, Zhicong Yang, Xiaotong Huang, Mingjin Liu, Yi Yin, Yushan Liu, Xiaoning Li, Zhihang Peng, Li-Qun Fang
| Nature Verified
Abstract While effectiveness of monovalent inactivated SARS-CoV-2 vaccines on preventing infection and severe disease has been well-characterized, their effectiveness on reducing infectivity of infected individuals and thereby blocking onward transmission to close contacts remains poorly understood.
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In Science Journals

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By Tianyu Zhu, Thomas Cottle, Anna M. Puszynska, Unnati Sonawala, Madeleine Seale, Phil Szuromi, Corinne N. Simonti, Michael Funk Verified, Jelena Stajic Verified, Yi Yin, Annalisa M. VanHook Verified, Jake Yeston Verified, Sacha Vignieri Verified, L. Bryan Ray Verified, Di Jiang, Priscilla Kelly Verified, Stella Hurtley Verified, Jesse R. Smith, Dorothy Hallberg, Christiana N. Fogg
| Science Magazine Verified
Plant Development How mirror-image flowers break symmetry Solar Cells A polymer replacement for fullerenes Ancient DNA Early South American smallpox Structural Biology Collagen structure revealed Physics Calculating Kondo Climatology Underestimated heat risk to rice yield Physiology RNA editing for stem cell health Organic Chemistry Easing fluoride into alcohols Marine Conservation Look to the past Biochemistry Make or break Bacterial Immunity RNA cleavage-based antiviral defense Biosynthesis...
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Obesity-driven microbial GABA depletion promotes metabolic rewiring and colorectal cancer progression

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By Wei Guo, Kaiyue Sun, Xia Wang, Mengmeng Li, Zheng Li, Yi Yin, Tengfei Ma, Yikun Li, Xiaoning Xu, Jianbo Liu, Jiahao Zhang, Panpan Feng, Ruijie Ma, Jiayi Ren, Jie Liu, Changan Liu, Xiang Gao, Dawei Chen, Jingxin Li, Xizan Yue, Cuiyu Zhang
| Nature Verified
Abstract Obesity is a major risk factor for colorectal cancer (CRC), yet the mechanisms linking obesity-associated gut dysbiosis to tumor progression remain unclear. Here, we show that a high-fat diet and fecal microbiota from patients with obesity-associated CRC deplete the GABA-producing commensal Bacteroides ovatus, resulting in reduced luminal GABA and accelerated tumorigenesis. Microbial GABA activates epithelial GABAB receptor signaling and induces TPI1 through the PI3K–HIF1α pathway.
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