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Yin-Ming Kuo on Muck Rack

Yin-Ming Kuo

As seen in: Wiley Online Library, The Journal of Biological Chemistry
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Articles

Engaging student opinions on vaccine development innovation: Experiences from a “Shark Tank” project

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By Jeffrey Barrett, Jeffrey Skolnik, Mary Jo Ingram, Yin-Ming Kuo
| Wiley Online Library Verified
WHAT IS THE CURRENT KNOWLEDGE ON THE TOPIC? Most curriculum in vaccine development use a standard didactic approach with content focused on immunology, vaccinology, and the stages of development. There has been little consideration for how artificial intelligence (AI) teaching approaches can be incorporated into teaching practices in general and especially in translational research courses. WHAT QUESTION DID THIS STUDY ADDRESS?
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Histone deacetylase 8 substrate selectivity is determined by long- and short-range interactions leading to enhanced reactivity for full-length histone substrates compared to peptides

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By Yin-Ming Kuo, Carol Ann Castaneda, Noah A. Wolfson, Katherine R. Leng
| The Journal of Biological Chemistry Verified
Author contributions: NAW and CAF designed the study. NAW designed the assays and performed the peptide and tetramer assays. NAW, CAC, and KRL purified proteins and performed octamer assays. CAC and KRL assembled nucleosomes and performed nucleosome assays. NAW, CAC, KRL, and CAF analyzed the data. Y-MK performed and AJA designed the histone mass spectrometry analysis. NAW, CAC, KRL, and CAF prepared the manuscript. All authors reviewed and approved the final manuscript.
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An Essential Role for the Tumor-Suppressor Merlin in Regulating Fatty Acid Synthesis

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By Yin-Ming Kuo, Dina S. Stepanova, Galina Semenova, Andrew J. Andrews
| cancerres.aacrjournals.org
AbstractNeurofibromatosis type 2 (NF2) is an autosomal dominant disorder characterized by the development of multiple tumors in the central nervous system, most notably schwannomas, and meningiomas. Mutational inactivation of the NF2 gene encoding the protein Merlin is found in most sporadic and inherited schwannomas, but the molecular mechanisms underlying neoplastic changes in schwannoma cells remain unclear.
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