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Yinghua Tang on Muck Rack

Yinghua Tang

As seen in: Nature, Canadian Journal of Infectious Diseases & Medical Microbiology, Dove Medical Press
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Articles

Amino acid-derived ionizable lipids enable inhaled base editing for therapeutic gene correction in the lung

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By Fanglin Gong, Yue Quan Xu, Jingan Chen, Shun Zhang, Songtao Dong, Lauren Healy, Breanna Y. Seto, Tyler Thomson, Yinghua Tang, Ziyan Chen, Andrew Varley, David Chen, Craig Hodges, Amy Wong, Jim C. Hu, Basil P. Hubbard, John F. Engelhardt, Ziying Yan, Bowen Li, Muye Zhou, Krista Antonio
| Nature Verified
Abstract CRISPR-based gene editing holds promise for treating genetic diseases, yet its application to lung disorders has been hindered by the challenges of pulmonary delivery. Inspired by the modularity and biocompatibility of amino acid-derived chemistries, we report the combinatorial synthesis of 960 ionizable lipids incorporating chemically diverse backbones from both proteinogenic and non-proteinogenic α-amino acids.
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The Association Between Adiponectin Gene Polymorphism (rs1501299) and | DMSO

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By Lianli Yin, Yinghua Tang, Yulin Yuan
| Dove Medical Press
Back to Journals » Diabetes, Metabolic Syndrome and Obesity » Volume 18 Authors Yin L , Tang Y , Yuan Y Received 10 July 2024 Accepted for publication 18 January 2025 Published 25 January 2025 Volume 2025:18 Pages 209—215 DOI https://doi.org/10.2147/DMSO.S475193 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 4 Editor who approved publication: Dr Rebecca Conway Lianli Yin,1 Yinghua Tang,2 Yulin Yuan1 1Department of Clinical Laboratory, Guangxi Academy...
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