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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Rational Design of Carbon Dot-Supported Mn─Zn Bimetallic Single-Atom Nanozymes for Enhancing SOD-Like Activity and Fluorescence
J.Li, Y.Xiang, Q.Zhang, et al. “Rational Design of Carbon Dot-Supported Mn─Zn Bimetallic Single-Atom Nanozymes for Enhancing SOD-Like Activity and Fluorescence.” Advanced Functional Materials (2026): e31973. https://doi.org/10.1002/adfm.202531973 Conflicts of Interest The authors declare no conflict of interest. Data Availability Statement The data that support the findings of this study are available in the supplementary material of this article.
SADS-CoV nsp1 inhibits the STAT1 phosphorylation by promoting K11/K48-linked polyubiquitination of JAK1 and blocks the STAT1 acetylation by degrading CBP
Abstract The newly discovered zoonotic coronavirus swine acute diarrhea syndrome coronavirus (SADS-CoV) causes acute diarrhea, vomiting, dehydration, and high mortality rates in newborn piglets. Although SADS-CoV uses different strategies to evade the host’s innate immune system, the specific mechanism(s) by which it blocks the interferon (IFN) response remains unidentified. In this study, the potential of SADS-CoV nonstructural proteins (nsp) to inhibit the IFN response was detected.
SADS‐CoV nsp1 inhibits the IFN‐β production by preventing TBK1 phosphorylation and inducing CBP degradation
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. REFERENCES 1, , . From SARS to SARS-CoV-2, insights on structure, pathogenicity and immunity aspects of pandemic human coronaviruses. Infect Genet Evol. 2020; 85:104502. 2, , , et al. Retrospective detection and phylogenetic analysis of swine acute diarrhoea syndrome coronavirus in pigs in southern China. Transbound Emerg Dis. 2019; 66(2): 687-695. 3, , , et al. A new Bat-HKU2-like coronavirus in Swine, China, 2017.
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