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Yinglu Guan on Muck Rack

Yinglu Guan

As seen in: The Journal of Clinical Investigation, Genes and Development Journal, Texas Medical Center
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Articles

Peroxisomal integrity in demyelination-associated microglia enables cellular debris clearance and myelin renewal in mice

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By Joseph A Barnes-Vélez, Xiaohong Zhang, Kiersten Scott, Yinglu Guan
| The Journal of Clinical Investigation
ResearchCell biologyInflammationNeuroscience Open Access | 10.1172/JCI179985 J Clin Invest. https://doi.org/10.1172/JCI179985. Copyright © 2025, Barnes-Vélez et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
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KLF5 Governs Sphingolipid Metabolism and Barrier Function of the Skin

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By Ying Lyu, Yinglu Guan, Lisa Deliu, Ericka Humphrey
| Texas Medical Center
Abstract Stem cells are fundamental units of tissue remodeling whose functions are dictated by lineage-specific transcription factors. Home to epidermal stem cells and their upward-stratifying progenies, skin relies on its secretory functions to form the outermost protective barrier, of which a transcriptional orchestrator has been elusive. KLF5 is a Krüppel-like transcription factor broadly involved in development and regeneration whose lineage specificity, if any, remains unclear.
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KLF5 governs sphingolipid metabolism and barrier function of the skin

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By Ying Lyu, Ericka Humphrey, Yinglu Guan, Lisa Deliu
| Genes and Development Journal
Ying Lyu1,8, Yinglu Guan1,8, Lisa Deliu1, Ericka Humphrey1, Joanna K. Frontera1, Youn Joo Yang1, Daniel Zamler1, Kun Hee Kim2, Vakul Mohanty2, Kevin Jin1,3, Virginia Liu1,3, Jinzhuang Dou2, Lucas J. Veillon2, Shwetha V. Kumar2, Philip L. Lorenzi2, Yang Chen1, Kathleen M.
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