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Yingnan Hou on Muck Rack

Yingnan Hou

As seen in: Nature, Frontiers, Royal Society of Chemistry, BioRxiv, Cell Press
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Articles

A conserved small RNA-generating gene cluster undergoes sequence diversification and contributes to plant immunity

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By Li Feng, Yingnan Hou, AmirAli Toghani, Zhixue Wang, Bozeng Tang, Hui Li, Yue Qiao, Yan Wang, Jian Hua, Jixian Zhai, Wenbo Ma, Nicola Atkinson
| Nature Verified
Abstract Small RNA-mediated gene silencing contributes to plant immunity. The secondary small interfering RNA (siRNA) pathway promotes defense by silencing target genes in invading fungal and oomycete pathogens. Many secondary siRNAs are derived from transcripts potentially encoding pentatricopeptide repeat (PPR) proteins. Here, we report that siRNA production is an ancient function of a conserved clade of PPR genes that undergo extensive within-species diversification.
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An Extracellular miRNA Reshapes Cell Wall Integrity to Prime Systemic Immunity in Tomato

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By Yue Qiao, Yu Xia, Jianfei Shi, Zihan Song, Liying Jin, Lijie Xuan, Haolin Yang, Xiang Yu, Haiyan Liu, Ali Zhang, Jinfeng Chen, Yingnan Hou, Ruoshi Wang
| Cell Press Verified
Research articleOnline nowOpen access Affiliations & Notes 1Shanghai Collaborative Innovation Center of Agri-Seeds/School of Agriculture & Biology, Shanghai Jiao Tong University, Shanghai 200240, China 2State Key Laboratory of Animal Biodiversity Conservation and Integrated Pest Management, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China Article Info Publication History: Received February 12, 2026; Revised May 5, 2026; Accepted June 4, 2026; Published online June 8,...
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Topological links in predicted protein complex structures reveal limitations of AlphaFold - Communications Biology

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By Yingnan Hou, Liuqing He, Liang Tao
| Nature Verified
Abstract AlphaFold is making great progress in protein structure prediction, not only for single-chain proteins but also for multi-chain protein complexes. When using AlphaFold-Multimer to predict protein‒protein complexes, we observed some unusual structures in which chains are looped around each other to form topologically intertwining links at the interface.
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