Yingwei Zhang
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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Mycobacterium tuberculosis IDH-PPARγ interaction suppresses GPX4 to drive macrophage ferroptosis and sustain persistent infection
Abstract Mycobacterium tuberculosis (M.tb) actively reprograms host lipid metabolism during infection; however, the underlying mechanism remains poorly understood. How M.tb manipulates macrophage lipid metabolism to induce lipid peroxidation and ferroptosis for bacterial persistence remains a fundamental question. Here, using single-cell RNA sequencing and proteomics, we show that M.tb infection substantially upregulates peroxisome proliferator-activated receptor gamma (PPARγ) in macrophages.
Pathology and Transcriptomic Characteristics of Skin Lesions Induced by Mpox Virus in Rabbit
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. References 1 and , “Monkeypox Virus,” Bacteriological Reviews 37, no. 1 (1973): 1–18. 2, , , et al., “Human Monkeypox,” Bulletin of the World Health Organization 46, no. 5 (1972): 569–576.
Clinical significance of radiological usual interstitial pneumonia pattern in primary Sjögren syndrome-associated interstitial lung disease
Abstract Background: The radiological usual interstitial pneumonia (UIP) pattern demonstrates heterogeneity across different underlying etiologies. This study aimed to characterize its clinical and prognostic impact in primary Sjögren’s syndrome-associated interstitial lung disease (pSS-ILD) and compare these features with those in idiopathic pulmonary fibrosis (IPF). Methods: Consecutive patients with pSS-ILD and IPF were enrolled.
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