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Yingying Guo

As seen in: Color Research & Application, Nature, Wiley Online Library, ScienceDirect, Annals of the Rheumatic Diseases, Frontiers, Journal of Business Research, MDPI, Technovation, The Conversation and
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Articles

Implicaciones pronósticas de la disfunción microvascular coronaria en el IAMCEST con y sin síndrome metabólico

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By Qian Guo, Yingying Guo, Shutian Shi
| Dialnet - Universidad de La Rioja
español Introducción y objetivos El síndrome metabólico (SMet) se asocia con la disfunción microvascular coronaria (DMC) y ambas entidades aumentan el riesgo de episodios cardiovasculares tras un infarto agudo de miocardio con elevación del segmento ST (IAMCEST). Sin embargo, la importancia de la DMC en pacientes con IAMCEST y SMet sigue sin estar clara.
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Self-assembled chamber-like cardiac organoids for modeling cardiac chamber formation and cardiotoxicity assessment

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By Xinle Zou, Fanwen Wang, Huilin Zheng, Tianci Kong, Rui Jiang, Yingying Guo, Yu Liang, Hanqing Zhao, Bo Wang, Duanqing Pei, Xianzhuang Liu
| Nature Verified
Abstract The human heart remains a central focus of biomedical research, yet capturing early chamber morphogenesis in vitro with structural and functional fidelity remains challenging. Here we show the generation of chamber-like cardiac organoids (CCOs) from human pluripotent stem cells that reproduce key features of heart chamber development. CCO formation is orchestrated by coordinated FGF, WNT, BMP, RA, and AA signaling, and regulated by transcription factors including HAND1, TFAP2B and NR2F2.
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Prognostic Implications of Coronary Microvascular Dysfunction in ST-Elevation Myocardial Infarction by Obesity Status

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By Christopher D. Byrne MD, Qian Guo, Yingying Guo
| Wiley Online Library Verified
BMI body mass index CMD coronary microvascular dysfunction CMR cardiac magnetic resonance IMH intramyocardial haemorrhage IMR index of microcirculatory resistance MACCE major adverse cardiovascular and cerebrovascular events MVO microvascular obstruction PPCI primary percutaneous coronary intervention STEMI ST-segment elevation myocardial infarction 1 Introduction The prevalence of obesity and overweight was 50.7% in the adult population in China [1], constituting a paramount public health...
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