Yingying Yue
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ROS-sensing transcription factor YchJ regulates RssB-RpoS pathway to protect Salmonella against oxidative attack by macrophages
Abstract Bacterial pathogens must overcome oxidative stress to survive within host phagocytes. Although canonical systems such as OxyR are well characterized, alternative pathways remain poorly understood. Here, we identified YchJ, a conserved yet uncharacterized protein, as a central redox-sensitive transcription factor that coordinates a major antioxidant defense system in Salmonella independently of OxyR.
Adjunctive role of p16/Ki-67 dual-stain cytology in colposcopy referral pathways for cervical precancer and persistent high-risk HPV infection
Abstract Background: This study aimed to evaluate the adjunctive triage performance of p16/Ki-67 dual staining (DS) cytology for cervical lesions in a colposcopy-referred cohort, to analyze its correlation with lesion severity, and to explore its predictive value for persistent high-risk human papillomavirus (HR-HPV) infection. Methods: A total of 109 patients undergoing colposcopic cervical biopsy (recruited via standard HPV+TCT referral criteria) were included.
Disruptions of p11(S100A10) and HPA axis homeostasis participate in th
Back to Journals » Neuropsychiatric Disease and Treatment » Volume 21 Authors Yue Y, Zhang J, Li Y, Ma X, Chen G, Zhu Z, Chen S , Chen Y, You L, Tan L, Jiang W, Yuan Y Received 25 June 2025 Accepted for publication 18 September 2025 Published 30 September 2025 Volume 2025:21 Pages 2237—2249 DOI https://doi.org/10.2147/NDT.S549538 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Yu-Ping Ning Yingying Yue,1,*...
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