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Yinlei Lei

As seen in: Wiley Online Library, Frontiers
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Articles

DNA hypomethylation of the OLFM1 gene in patients with depression

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By Chen Zhou, Tiantian Zou, Ming Zhao, Xinrui Guo, Jia En Wang, Yinlei Lei, Yinghan Li, Liping Hu, Linlin Liu, Lili Qing, Wensa Yin, Shengjie Nie
| Frontiers
Abstract Objective: Depression is a heterogeneous psychiatric disorder and a growing public health concern, characterized by its high prevalence, recurrence rate, and association with suicide. There is evidence suggesting that both genetic susceptibility and environmental factors can regulate gene expression through DNA methylation, thereby influencing the occurrence and development of depression. The olfactory sensory neuropeptide 1 (OLFM1) protein is a risk factor for mental disorders.
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The emerging role of IL‐38 in diseases: A comprehensive review

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By Weijun Chen, Yong Ke, Shuangyun Xi, Yinlei Lei
| Wiley Online Library Verified
1 OVERVIEW OF INTERLEUKIN-38 (IL-38) The IL-1 family includes 11 cytokine members, in which IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β, and IL-36γ have agonist activity, IL-1Ra and IL-36Ra are antagonists of receptors, and IL-37 and IL-38 exert anti-inflammatory functions.1, 2 IL-38 was first discovered in 2001 and was called IL-1HY2 or IL-1F10 at that time.
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