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Efficacy and safety of traditional Chinese medicine herbal hand-foot bath combined with arnebia oil for chemotherapy-induced hand-foot syndrome refractory to standard treatment: a single-arm prospective interventional pilot study of 30 cases
Abstract Background: Chemotherapy-induced hand-foot syndrome (HFS) is a common dose-limiting cutaneous adverse reaction associated with cytotoxic agents such as capecitabine and small-molecule targeted drugs. Severe HFS may lead to dose reduction or interruption of antitumor treatment, significantly impairing patients' quality of life and treatment compliance.
PD-1 blockade combined with anlotinib and bicalutamide for metastatic primary cutaneous apocrine carcinoma: a case report and literature review
Abstract Background: Primary cutaneous apocrine carcinoma (PCAC) is a rare malignant adnexal tumor with substantial diagnostic complexity and no established systemic therapy standard for advanced disease.Evidence for endocrine therapy, targeted therapy, and immune checkpoint inhibitors is limited to small series and case reports. Case presentation: A patient presented with a pruritic erythematous plaque on the left chest wall that progressively enlarged over one year.
Frontiers | Donafenib intolerance in hepatocellular carcinoma: severe hand-foot skin reaction and successful switch to lenvatinib - a case report and literature review
CASE REPORT article Volume 15 - 2025 | https://doi.org/10.3389/fonc.2025.1728098 This article is part of the Research TopicDrug Repurposing: The New Frontier in Fighting CancerView all 3 articles Introduction Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, and many patients present at stages unsuitable for curative surgery or ablation (1, 2). For these patients, systemic therapy is central to care.
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