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Yoko Shiba

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Articles

Molecular Detection of Membrane Damage in Mammalian Cells

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By Yoko Shiba, Nana Saito
| preprints.org
This open access article is published under a , which permit the free download, distribution, and reuse, provided that the author and preprint are cited in any reuse.
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Molecular Detection of Membrane Damage: Lessons from Bacteria

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By Yoko Shiba, Nana Saito
| preprints.org
Mammalian cells contain many membranous organelles, among which endosomes are the initial destination for endocytosed materials. Drugs and pathogens, such as bacteria, are internalized by cells and transported to endosomes or phagosomes, then to lysosomes for degradation. Internalized drugs must escape from endosomes into the cytosol before undergoing degradation in lysosomes. However, endosomal escape is often inefficient in artificial drug delivery systems (DDSs).
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ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation

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By Subhajit Poddar, Samuel D. Chauvin, Christopher Archer, Wei Qian, Jean A. Castillo-Badillo, Xin Yin, Cathrine Miner, Joe Holley, Teresa V. Naismith, Xiaochao Wei, Yue Ning, Jiayuan Fu, Nehalee Surve, Shivam A. Zaver, Kimberly A. Wodzanowski, Katherine R. Balka, Canyu Liu, Will Bailis, Sara Cherry, Clay F. Semenkovich, Dominic De Nardo, Sunnie M. Yoh, Sumit K. Chanda, David Kast, Jonathan J. Miner, W. Miguel Disbennett, W. Alexander Stinson, Trini A. Ochoa, Rajan Venkatraman, Yoko Shiba, Elisha D.O. Roberson
| Cell Press Verified
1Division of Rheumatology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA 2Department of Cell Biology and Physiology, Washington University School of Medicine, St Louis, MO 63110, USA 3Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA 4Immunity and Pathogenesis Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA 5State Key Laboratory of Veterinary...
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