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HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion
STAR★Methods REAGENT or RESOURCESOURCEIDENTIFIER Antibodies 112Cd Rat Anti mouse CD45 BioLegend Clone:30-F11; Cat#103120; RRID: AB_312985 113In anti-mouse/human CD44 BioLegend Clone:IM7; Cat#103014; RRID: AB_312965 115In Rat anti-mouse CD3 BioLegend Clone: 145-2C11; Cat#100340; RRID: AB_11149115 141Pr Rat anti-mouse CD274 BioLegend Clone:10F.9G2; Cat#124302; RRID: AB_961228 142Nd Ratr anti-mouse Ly-6G/Ly-6C (Gr-1) BioLegend Clone: RB6-8C5; Cat#108449; RRID: AB_2563785 143Nd Ratr anti-mouse...
pH variations enable guanine crystal formation within iridosomes - Nature Chemical Biology
Abstract Many animals produce vivid colors by reflecting and amplifying light with stacked guanine crystals within membrane-bound organelles called iridosomes. While the presence of guanine crystals in iridosomes is well documented, the mechanisms facilitating the accumulation of water-insoluble guanine and driving its crystallization remain unclear.
Specialized Molecular Pathways Drive the Formation of Light-Scattering Assemblies in Leucophores
Abstract Pigmentation plays a vital role in the survival of organisms, supporting functions such as camouflage, communication, and mate attraction. In vertebrates, these functions are mediated by specialized pigment cells known as chromatophores of which, uric acid crystal-forming leucophores remain the least understood, with little known about their molecular mechanisms.
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