Yuying Huang
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Sensory neuron BRAF mediates opioid-induced hyperalgesia and tolerance via presynaptic NMDA receptor hyperactivity
ResearchNeuroscienceOncology Open Access | 10.1172/JCI201808 J Clin Invest. https://doi.org/10.1172/JCI201808. Copyright © 2026, Jin et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. View PDF Abstract Opioids are essential analgesics for managing severe pain but can paradoxically increase pain sensitivity (hyperalgesia) and diminish analgesic efficacy (tolerance).
Fully Bayesian Sequential Design for Heteroscedastic Stochastic Simulations
Advanced search Technometrics Latest Articles Submit an article Journal homepage Full Article Figures & data References Supplemental Citations Metrics Reprints & Permissions Read this article /doi/full/10.1080/00401706.2026.2703239?needAccess=true Accepted author version Abstract We present a fully Bayesian sequential strategy for predicting the mean response surface of heteroscedastic stochastic simulation models.
Iron drives protease-independent cleavage of gasdermin D in allergic airway diseases
Keywords gasdermin D iron metabolism protease-activated receptor 1 PAR1 ferritinophagy poly(rC)-binding protein 2 PCBP2 interlunkin-33 type 2 immunity Get full text access Log in, subscribe or purchase for full access. References 1. Drake, L.Y. ∙ Kita, H. IL-33: biological properties, functions, and roles in airway disease Immunol. Rev. 2017; 278:173-184 2. Hardman, C. ∙ Ogg, G. Interleukin-33, friend and foe in type-2 immune responses Curr. Opin. Immunol. 2016; 42:16-24 3. Chen, W. ∙ Chen, S. ∙ Yan, C. ...
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