Zacharia Schwartz on Muck Rack

Zacharia Schwartz

As seen in: Nature
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Articles

SIRT6 overexpression counteracts chromatin aging in the male murine liver

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By Ron Nagar, Zacharia Schwartz, Almog Katz, Noga Touitou, Efrat Sharon, Kobi Tzdaka, Odeya Waner, Noam Shalev, Rotem Clo, Leah Weiss, Benjamin Epstein, Michel Bernier, Roni B Shtark, Nirad Banskota, Kwan-Wood G. Lam, Supriyo De, Nathan Price, Batia Lerrer, Daniel Bar, Rafael de Cabo, Haim Cohen
| Nature
Abstract Aging is associated with detrimental changes in chromatin structure and gene expression, contributing to inflammation, metabolic decline and tissue dysfunction. SIRT6, a histone deacetylase, plays a key role in maintaining chromatin integrity and promoting longevity.
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