Zahida Yesmin Roly on Muck Rack

Zahida Yesmin Roly

As seen in: Cell Press
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Articles

Insights into Gonadal Sex Differentiation Provided by Single-Cell Transcriptomics in the Chicken Embryo

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By Sarah C.P. Williams, Martin Andres Estermann, Claire Elizabeth Hirst, Zahida Yesmin Roly
| Cell Reports Verified
Highlights • Chicken gonadal supporting cell lineage is not derived from the coelomic epithelium • Chicken supporting cells derive from a DMRT1+/OSR1+/PAX2+/WNT4+ mesenchyme population • PAX2 is a novel marker of undifferentiated supporting cell progenitors in chicken • Chicken steroidogenic cells derive from pre-differentiated supporting cells Summary Although the genetic triggers for gonadal sex differentiation vary across species, the cell biology of gonadal development was long thought to...
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