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Zhinang Yin

As seen in: Wiley Online Library, Genome Biology, Science Magazine, Cell Press, Cell Stem Cell, Genome Research
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Articles

KAT6A chimeras form a self-reinforcing epigenetic module with NURF and MLL/COMPASS to sustain AML - Genome Biology

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By Junhui Lv, Zhinang Yin, Conghui Li, Honglin Wen, Jian Ni, Peiyuan Yang, Zemin Song, Ying Xiang, Honghong Wang, Rui Lu, Li Huang, Ying Zhou, Hai-Bing Zhou, Ruijing Xiao, Pingping Fang, Kaiwei Liang
| Genome Biology Verified
HEK293T (ATCC CRL-3216) and Mouse Embryonic Fibroblast (MEF; ATCC CRL-2752) cells were cultured in high-glucose DMEM (Life Technologies) supplemented with 10% FBS (LONSERA S711-001), 1% penicillin/streptomycin (Gibco), and L-glutamine (Gibco) at 37 °C in a 5% CO2 atmosphere. Drosophila S2 cells (Gibco R69007) from Invitrogen were maintained in Schneider's medium (Sigma-Aldrich) at 25 °C.
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Mechano-oncogenic cytoskeletal remodeling drives leukemic transformation with mitochondrial vesicle-mediated STING activation

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By Yali Cui, Lilan Xin, Ruijing Xiao, Jingjing Feng, Conghui Li, Zhinang Yin, Honghong Wang, Qiuzi Li, Mengxuan Wang, Yiming Zhang, Ying Zhou, Li Huang, Xiaoqing Li, Xiaoyan Liu, Shangqin Liu, Fuling Zhou, Zheng Liu, Hai-Bing Zhou, Pingping Fang, Kaiwei Liang, Zemin Song, Baoyi Lin
| Cell Stem Cell Verified
Keywords cytoskeletal co-option of mitochondrial constriction CCMC CBFβ-SMMHC hematopoietic stem and progenitor cells HSPCs cytoskeleton mitochondrial-derived vesicle MDV cGAS-STING signaling Get full text access Log in, subscribe or purchase for full access. References 1. Papaemmanuil, E. ∙ Gerstung, M. ∙ Bullinger, L. ... Genomic classification and prognosis in acute myeloid leukemia N. Engl. J. Med. 2016; 374:2209-2221 2. Döhner, H. ∙ Wei, A.H. ∙ Löwenberg, B. Towards precision medicine for AML Nat. Rev.
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The phosphatase PP1 sustains global transcription by promoting RNA polymerase II pause release

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By Zhenning Wang, Aixia Song, Bolin Tao, Jingwen Wang, Zhinang Yin, Ruijing Xiao, Xinwen Zhou, Xue-Ying Shang, Shibin Hu, Kaiwei Liang, Charles G Danko, fei chen, Maojian Miao, Yi-Qing Luo
| Cell Press Verified
Keywords PP1 PNUTS PNUTS-PP1 PP2A INTAC phosphatase RNA polymerase II transcription pausing 7SK snRNP Get full text access Log in, subscribe or purchase for full access. References 1. Jonkers, I. ∙ Lis, J.T. Getting up to speed with transcription elongation by RNA polymerase II Nat. Rev. Mol. Cell Biol. 2015; 16:167-177 2. Chen, F.X. ∙ Smith, E.R. ∙ Shilatifard, A. Born to run: control of transcription elongation by RNA polymerase II Nat. Rev. Mol. Cell Biol. 2018; 19:464-478 3. Cramer, P.
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