Ziyin Li
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NuSAP1 promotes spindle assembly in Trypanosoma brucei by bundling spindle microtubules
Abstract The parasitic protozoan Trypanosoma brucei assembles an intranuclear spindle during mitosis to segregate its chromosomes through mechanisms that are distinct from its mammalian host. This parasite employs unusual nucleus- and spindle-associated proteins (NuSAPs) to regulate mitosis, but their mechanistic roles remain poorly understood. Here, we characterized NuSAP1 and analyzed the functional interplay of NuSAP1 with its interacting and proximal proteins.
Intra- and peritumoral radiomics for predicting equivocal HER2 status of breast cancer on contrast-enhanced mammography
Abstract Objective: Identification of Human epidermal growth factor receptor 2 (HER2) status is significant for the treatment and prognosis of breast cancer patients. The study aimed to evaluate the equivocal HER2 (IHC 2+) status of breast cancer using intra- and peritumoral radiomics features of contrast-enhanced mammography (CEM).
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