Ziying Liu
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The methylation pattern of osimertinib resistance: prospects for diagnosis and treatment of NSCLC
Abstract Osimertinib, a third-generation EGFR-TKI, is effective for non-small cell lung cancer (NSCLC), but drug resistance significantly worsens patient outcomes. Epigenetic regulation, particularly methylation, is crucial in tumor progression and resistance development. Changes in polygenic methylation patterns are linked to osimertinib resistance in NSCLC, affecting drug target mutations, transporter functions, and signaling pathways.
Author Correction: An atlas of genetic effects on cellular composition of the tumor microenvironment
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Correction to: Nature Immunology https://doi.org/10.1038/s41590-024-01945-3, published online 2 September 2024. In the version of the article initially published, the tumor growth curve for the shControl and shCCL2 group in Fig. 7h was generated using incorrect tumor volume data. The authors have corrected the corresponding Source Data and generated an updated Fig. 7h. During the preparation of the Source Data for Fig.
By Yimin Cai, Zequn Lu, Can Chen, Ying Zhu, Zhirui Chen, Jingyi Peng, Xuanyu Zhu, Ziying Liu, Ming Zhang, Jinyu Huang, Yanmin Li, Yizhuo Liu, Qianying Ma, Chunyi He, Shuoni Chen, Wen Tian, Caibo Ning, Hui Geng, Bin Xu Verified, Haijie Li, Xu Zhu, Jun Fang, Xiaoyang Wang, Shaokai Zhang, Meng Jin, Chaoqun Huang, Xiaojun Yang, Jianbo Tian, Xiaoping Miao, Zuyou Wu, Linyun Fan
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Nature
Verified
Jasmonate, salicylate, and ethylene-responsive transcriptomics discovery in spikelets of three wheat genotypes reveals a rapid and conserved response for jasmonate signaling
?Mathematical formulae have been encoded as MathML and are displayed in this HTML version using MathJax in order to improve their display. Uncheck the box to turn MathJax off. This feature requires Javascript. Click on a formula to zoom. ABSTRACT The accumulation of plant hormones in different tissues leads to transcriptional reprogramming that guides the downstream phenotypic response.
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