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ArticleVolume 7, Issue 2102611Open access Affiliations & Notes 1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA 2Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA 3Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA 4Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA...
Keywords liver single nucleus chromatin accessibility expression multiome quantitative trait loci caQTL eQTL cardiometabolic lipid cholesterol hepatocyte liver sinusoidal endothelial cell Introduction Genome-wide association studies (GWASs) have identified hundreds of signals for cardiometabolic traits,1,2,3,4,5,6 but the molecular mechanisms and cell type(s) of action for most of these signals have not yet been defined.
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