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Anna Baranska on Muck Rack

Anna Baranska

As seen in: Cell Reports
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Articles

GM-CSF and specific type 2 cytokines induce CD103+ and CD301b+ cell states in cDC1s and cDC2s

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By Lukas Amon, Damir Vurnek, Anna Seichter, Giorgi Tchitashvili, Tomasz Kaszubowski, Nincy Debeuf, Tina Vogler, Lukas Lächele, Anna Baranska, Stella E. Autenrieth, Falk Nimmerjahn, Kai Hildner, Klaus Pfeffer, Barbara U. Schraml, Lukas Heger, Bart N. Lambrecht, Christian Lehmann, Diana Dudziak, Markus Mroz, Nicole Küpper, Kaushikk Ravi Rengarajan, Nounagnon R. Tochoedo
| Cell Reports Verified
Keywords conventional dendritic cells ontogeny cell state CD103+ cDC1 CD301b+ cDC2 DC2 and DC3 progenitor heterogeneity type 2 cytokines CD301b GM-CSF Research topic(s) CP: immunology Introduction Conventional dendritic cells (cDCs) represent central orchestrators of immune responses. cDCs were classified based on ontogeny, phenotype, and function into cDC1s and cDC2s across murine and human tissues.1 They arise from hematopoietic stem cells (HSCs) located in bone marrow.
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Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal

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By Aix Marseille Université, Alaa Shawket, Anna Baranska, Cnrs Umr
| jem.rupress.org
AbstractHere we describe a new mouse model that exploits the pattern of expression of the high-affinity IgG receptor (CD64) and allows diphtheria toxin (DT)–mediated ablation of tissue-resident macrophages and monocyte-derived cells. We found that the myeloid cells of the ear skin dermis are dominated by DT-sensitive, melanin-laden cells that have been missed in previous studies and correspond to macrophages that have ingested melanosomes from neighboring melanocytes.
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