Skip To Main Content
Bart Westerman on Muck Rack

Bart Westerman

As seen in: Nature, Cell Press, medRxiv
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Bart

Contact Bart, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Challenges to determine synergistic drug interactions in mice - Nature Communications

|
By Bart Westerman, Yoran Broersma, Peter Sminia
| Nature Verified
arising from R. S. Narayan et al. Nature Communications https://doi.org/10.1038/s41467-020-16735-2 (2020) Synergistic drug interactions can be assessed in a laboratory setting by multiple methods that do not necessarily lead to the same outcome; hence, the optimal way to determine synergy is a matter of an ongoing debate.
Open in Who Shared Issue with article?

Evolutionary trajectories of IDH-mutant astrocytoma identify molecular grading markers related to cell cycling - Nature Cancer

|
By Wies R Vallentgoed, Youri Hoogstrate, Levi van Hijfte, Erik van Dijk, Anna Lavrova, Marcel Bühler, Wolfgang Wick, Michael Weller, Tobias Weiss, Marion Smits, Bauke Ylstra, Bart Westerman, Pieter Wesseling
| Nature Verified
Abstract The evolutionary processes that drive malignant progression of IDH-mutant astrocytomas remain unclear. Here, we performed multiomics on matched initial and recurrent tumor samples from a cohort of 105 patients and overlaid the data with detailed clinical annotation. We identified overlapping features associated with malignant progression that are derived from three molecular mechanisms: cell cycling, tumor cell (de)differentiation and remodeling of the extracellular matrix.
Open in Who Shared Issue with article?

The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeutic targets

|
By Jaco C. Knol, Mengge Lyu, Franziska Böttger, Madalena Nunes Monteiro, Thang V. Pham, Frank Rolfs, Andrea Vallés-Martí, Tim Schelfhorst, Irene V. Bijnsdorp, Shuaiyao Wang, Fangfei Zhang, Bart Westerman, Barbara Sitek, Janne Lehtiö, Jan Koster, Jan IJzermans, Maarten F. Bijlsma, Jan Paul Medema, Alex A. Henneman, Sander R. Piersma, Ruud H Brakenhoff, Jacqueline Cloos, Valentina Cordo', Daphne de Jong, Geert Kazemier, Danijela Koppers-Lalic, Mariette Labots, John Martens, Jules P.P. Meijerink, Madiha Mumtaz, Chantal Scheepbouwer, Robby E. Kibbelaar, David P. Noske, Renske D.M. Steenbergen, Winan van Houdt, Elisa Giovannetti, Jos Jonkers, tong liu, Meisi Yan, Xiaolu Zhan, Tiannan Guo, Connie R. Jimenez
| Cell Press Verified
1Amsterdam UMC, location Vrije Universiteit Amsterdam, Department of Medical Oncology, OncoProteomics Laboratory, De Boelelaan 1117, Amsterdam, the Netherlands 2Cancer Center Amsterdam, Imaging and Biomarkers, Amsterdam, the Netherlands 3School of Medicine, Westlake University, Hangzhou, Zhejiang, China 4Westlake Center for Intelligent Proteomics, Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China 5Amsterdam UMC location Vrije Universiteit Amsterdam, Department of...
Open in Who Shared Issue with article?
See all 5 articles