Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Benjamin Klein
Sex-Based Differences in Acute and Long-Term Outcomes After Orbital Atherectomy for Severely Calcified Coronary Lesions: A Real-World Analysis
1. Vaduganathan M, Mensah GA, Turco JV, Fuster V, Roth GA. The global burden of cardiovascular diseases and risk: a compass for future health. J Am Coll Cardiol. 2022;80(25):2361-2371. doi:10.1016/j.jacc.2022.11.005 2. Sambola A, Del Blanco BG, Kunadian V, et al. Sex-based differences in percutaneous coronary intervention outcomes in patients with ischaemic heart disease. Eur Cardiol. 2023;18:e06. doi:10.15420/ecr.2022.24 3. Iwańczyk S, Dit Al Hakim SA, Skrzypińska M,.
TWEAK signaling drives the transition from psoriasis to atopic dermatitis–like inflammation in paradoxical eczema
|
Reference #1 Abstract Supplementary Materials REFERENCES AND NOTES eLetters (0) Information & Authors Metrics & Citations Check Access References Figures Tables Media Share This article has 0 eLetter . Abstract Targeted biologics have transformed the treatment of inflammatory skin diseases such as plaque psoriasis. However, some patients with psoriasis paradoxically develop eczematous skin reactions after therapy targeting tumor necrosis factor (TNF), interleukin-17 (IL-17), or IL-23.
By Sahiti Marella, Rachael Bogle, Haihan Zhang, Jennifer Fox, Joseph Kirma, Xianying Xing, Benjamin Klein, Vincent van Drongelen, Fadia Zagairy, Mira Hamed, Michael Ziv, Rundong Jiang, Poulami Dey, Allison C. Billi, Lam C Tsoi, Johann E. Gudjonsson, Eran Barak, Zoey Feister, Maya Liaks, Joanne Michelle Kahlenberg
|
Science Magazine
Verified
Myeloid infiltration and epidermal dysregulation characterize cutaneous photosensitivity in systemic lupus erythematosus
|
Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share This article has 0 eLetter . Abstract For patients with systemic lupus erythematosus (SLE), sun avoidance and sunscreen use are the only preventive therapies for photosensitivity, a process by which exposure to ultraviolet (UV) light triggers cutaneous and systemic flares of disease.
By Mitra P. Maz, Yuli Chen, Shajila Siricilla, Lin Zhang, Feiyang Ma, Mehrnaz Gharaee-Kermani, Benjamin Klein, Nguyen NGUYEN, NGuyen nguyen, Yuli Cai, Shannon Loftus, Allison C. Billi, Lisa Abernathy-Close, Moriah Ma, Rachael Bogle, Amy Hurst, Lam C Tsoi, Johann E. Gudjonsson, J. Michelle Kahlenberg, Rezvan Moallemian
|
Science Magazine
Verified
The speed problem: How frontier AI exposes weakness in enterprise cybersecurity
Attackers now move at machine speed, but organizations make decisions at committee speed. To close the gap, businesses need a different operating model and committed executive leadership. There has been an important shift in enterprise cybersecurity, and it is not the arrival of more sophisticated malware. It is the collapse of time.
netflix / void-model like 244 Follow Netflix 249
VOID removes objects from videos along with all interactions they induce on the scene β not just secondary effects like shadows and reflections, but physical interactions like objects falling when a person is removed. Project Page | Paper | GitHub | Demo Quick Start The included notebook handles setup, downloads models, runs inference on a sample video, and displays the result. Requires a GPU with 40GB+ VRAM (e.g., A100).
“Five Eyes” Nations Release Bribery Indicators Guidance and Other Cross-Border Anti-Corruption Cooperation Developments
The International Foreign Bribery Taskforce (“IFBT”) recently released its first-ever “Indicators of Foreign Bribery” guidance intended to help organizations in high-risk sectors, the broader business community, and the general public detect and address foreign bribery risks.[1] While the indicators do not substantively redefine the foreign bribery offense and will be familiar to many legal and compliance professionals, they represent an additional step forward in the international...
White House Announces New DOJ Fraud Division to Be Directly Supervised by the President
On January 8, 2026, the Vice President announced the creation of a new division for “national fraud enforcement” within the Department of Justice (“DOJ”).
Deploying agentic AI with safety and security: A playbook for technology leaders
This article is a collaborative effort by Benjamin Klein, Charlie Lewis and Rich Isenberg, with Dante Gabrielli, Helen Möllering, Raphael Engler, and Vincent Yuan, representing views from McKinsey’s Risk & Resilience Practice, Knowledge Partner of the upcoming RiskMinds International event in London. Business leaders are rushing to embrace agentic AI, and it’s easy to understand why.
Deploying agentic AI with safety and security: A playbook for technology leaders
Autonomous AI agents present a new world of opportunity—and an array of novel and complex risks and vulnerabilities that require attention and action now. Business leaders are rushing to embrace agentic AI, and it’s easy to understand why. Autonomous and goal driven, agentic AI systems are able to reason, plan, act, and adapt without human oversight—powerful new capabilities that could help organizations capture the potential unleashed by gen AI by radically reinventing the way they operate.
Deploying agentic AI with safety and security: A playbook for technology leaders
Autonomous AI agents present a new world of opportunity—and an array of novel and complex risks and vulnerabilities that require attention and action now. Business leaders are rushing to embrace agentic AI, and it’s easy to understand why. Autonomous and goal driven, agentic AI systems are able to reason, plan, act, and adapt without human oversight—powerful new capabilities that could help organizations capture the potential unleashed by gen AI by radically reinventing the way they operate.
Elmira man arrested for allegedly uploading child porn to the internet
ELMIRA, N.Y. (WENY) -- Elmira police announced on Wednesday, Oct. 8th that a 33-year-old Elmira man has been arrested for allegedly uploading child porn to the internet. Police say they served a search warrant at the home of Skyelar Williamson on October 6th.
Food truck rally coming to Thorne St. Park in Horseheads Original
HORSEHEADS, N.Y. (WENY) -- Food trucks have exploded in popularity in recent years, and now it appears the Southern Tier is getting in on the act. The Village of Horseheads announced on Friday, Oct. 3rd it is hosting the Great Fall Food Fest with food trucks from across the region.
Authorities ask for public's help in locating 53-year-old Bath woman
BATH, N.Y. (WENY) -- The Village of Bath Police Department is asking for the public's help locating 53-year-old Nikki Wright of Bath. The announcement was made on Friday, Oct. 3rd, and according to police, she was last accounted for on Sept. 16th. Police say she was last known to be traveling to Rochester. She is described by police as a black woman, 5'7, 160 pounds with brown eyes and black hair.
New York issues temporary burn ban, Pennsylvania urges people to use caution
TWIN TIERS (WENY) -- New York State announced a temporary burn ban on Thursday, Oct. 2nd with much of the state in drought conditions, while Pennsylvania is urging people to use caution to prevent wildfires. According to the New York Department of Conservation, all of New York outside of New York City and Westchester County.
Press Play: DOJ Ends FCPA Enforcement Pause, Offers New Guidelines for Companies
U.S. Department of Justice building in Washington, D.C. Photo: Diego M. Radzinschi/ALM
QRICH1 mediates an intracellular checkpoint for CD8+ T cell activation via the CARD11 signalosome
Editor’s summary T cell signaling is a carefully orchestrated series of molecular interactions that translate T cell receptor (TCR) engagement to gene expression changes that influence function. Carter et al. define a role for glutamine-rich protein 1 (QRICH1) in TCR signal transduction through regulation of the caspase recruitment domain–containing protein 11 (CARD11) signaling scaffold.
ATF4 drives regulatory T cell functional specification in homeostasis and obesity
Editor’s summary Regulatory T cells (Tregs) play an important role during homeostasis and are enriched in the liver in obesity-induced liver disease. Wang et al. explore how functional specification of liver Tregs is transcriptionally regulated in Western diet–induced obese mice. Effector Tregs expressing the transcription factor ATF4 accumulated in the livers of obese mice and promoted obesity-related liver fibrosis through integrin αvβ8–mediated activation of transforming growth factor–β.
O problema da velocidade: como a IA de fronteira expõe fragilidades na cibersegurança corporativa
Os atacantes cibernéticos hoje operam na velocidade das máquinas, enquanto as organizações decidem na velocidade dos comitês. Para eliminar esse descompasso, as empresas precisam de um modelo operacional diferente e de uma liderança executiva resoluta. Houve uma mudança significativa na cibersegurança corporativa, e não se trata do surgimento de malwares mais sofisticados, e sim da compressão do tempo.
MBPeace treaty: How myelin self-peptides broker CNS tolerance
Editors' Choice FOCIS HIGHLIGHTS Isabelle Leo https://orcid.org/0000-0002-7627-6690 and Etienne Caron etienne.caron@yale.eduAuthors Info & Affiliations Science Immunology 7 Mar 2025 Vol 10, Issue 105 Abstract Specific MBP-derived self-peptides promote immune tolerance in the CNS and induce an unconventional regulatory T cell response.
Trouble at the border: An invading gut bacterium can break tolerance to self-RNA
Abstract Mouse anti-RNA antibodies triggered by gut E. gallinarum correlate with self-RNA autoantibodies and lupus severity in humans. SIGN UP FOR FIRST RELEASE ALERTS Get the latest First Release papers from Science delivered right to you Some gut bacteria can translocate across the intestinal wall and travel to the lymph nodes, liver, and spleen, triggering systemic inflammation.
Dynamic STING repression orchestrates immune cell development and function
Editor’s summary The cyclic dinucleotide sensor stimulator of interferon genes (STING) is primarily known for its role in inducing type I interferon during infection and disease, but STING’s homeostatic functions are not well understood. By generating STING reporter mice, Knox et al. investigated the patterns of STING expression across tissues and immune cell types in healthy mice.
Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity
Editor’s summary Autoimmune photosensitivity is a common symptom of type I interferon (IFN)–driven skin diseases like cutaneous lupus erythematosus (CLE). Mechanisms mediating this response have been linked to ultraviolet B (UVB) light–induced mitochondrial damage in keratinocytes. Klein et al. show that mitochondrial Z-DNA accumulates and is released by CLE keratinocytes upon UVB light exposure.
Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate
Editor’s summary In response to chronic infections and cancer, CD8 T cells differentiate into an exhausted T (Tex) cell phenotype that exhibits suboptimal effector activity. The transcription factor TOX is critical for Tex differentiation, but it is unclear whether TOX is necessary to maintain this cell state after it is established. Huang et al. inducibly ablated TOX from committed virus-specific Tex cells in a mouse model of chronic lymphocytic choriomeningitis virus infection.
First Baptist Church demo in Elmira completed
Published February 19, 2025 11:09 AM By Benjamin C. Klein Click here for updates on this story ELMIRA, N.Y. (WENY) — The First Baptist Church was completely removed by demo crews as of Monday, Feb. 17th following a fire that destroyed much of the former church the week before. The fire happened on Thursday, February 13th, where a massive fire destroyed much of the church, leaving only some of the brick exterior.
Functional differences between rodent and human PD-1 linked to evolutionary divergence
Editor’s summary Preclinical studies in mice have been critical to understanding how the inhibitory receptor PD-1 functions. However, human and murine PD-1 share less than 60% amino acid identity. Masubuchi et al. found that human PD-1 was more inhibitory compared with murine PD-1 because of stronger binding interactions with its ligands PD-L1 and PD-L2 and more effective recruitment of the Shp2 phosphatase.
Type I interferon governs immunometabolic checkpoints that coordinate inflammation during Staphylococcal infection
Highlights • Staggered TLR and IFNAR signaling guide MRSA-induced metabolic remodeling in macrophages • Infection-induced NO⋅ disrupts the respiratory chain modulating IL-1β and IFN-β production • Histone lactylation represses Nos2 and limits NO⋅-driven IFN-β production • Chronic type I IFN blunts histone lactylation Summary Macrophage metabolic plasticity is central to inflammatory programming, yet mechanisms of coordinating metabolic and inflammatory programs during infection are poorly...
DOJ Launches New Whistleblower Program Focused on Corporate Misconduct
|
On August 1, 2024, the U.S. Department of Justice’s Criminal Division (“DOJ” or “Department”) launched a new Corporate Whistleblower Awards Pilot Program (the “Whistleblower Pilot Program” or the “Pilot Program”).[1] Under the Pilot Program, eligible whistleblowers who provide the Criminal Division with original and truthful information about certain types of corporate misconduct are eligible to receive a portion of a criminal or civil forfeiture exceeding $1 million.
By L. Atkinson, H. Christopher Boehning, Walter Brown, Jessica Carey, John Carlin Verified, Roberto Finzi, Harris Fischman, Melinda Haag, Brad S. Karp, Loretta Lynch, Mark F. Mendelsohn, Lorin L. Reisner, David Kessler, Benjamin Klein, Samuel Kleiner, Justin Lerer, Andrew Fishman, Liliana Ramírez Verified, Jacob Wellner
|
Lexology
Verified
Congress Quietly Amends FEPA: What Cos. Should Do Now
By Mark Mendelsohn and Benjamin Klein (July 26, 2024, 2:23 PM EDT) -- In December 2023, Congress passed its initial version of the Foreign Extortion Prevention Act,[1] the long-awaited companion to the U.S. Foreign Corrupt Practices Act that extended criminal liability to foreign government officials who demand or receive improper payments from U.S. persons or while in U.S. territory.... Law360 is on it, so you are, too.
Watkins Glen gets $4.6 million in Federal Funding for water infrastructure
Welcome to NewsBreak, an open platform where diverse perspectives converge. Most of our content comes from established publications and journalists, as well as from our extensive network of tens of thousands of creators who contribute to our platform. We empower individuals to share insightful viewpoints through short posts and comments.
Managing Allergies in The Summer: Tips For Dealing With Pollen and Other Allergens
The summertime is often a wonderful time for doing things outside, but it's also the worst time of year for people who suffer from allergies. Individuals with allergies may experience symptoms such as sneezing, itchy eyes, and a runny nose when the weather is warm because warm weather brings an increase in the amount of pollen and other allergens. However, there are measures that can be taken to reduce your contact with these irritants and protect yourself from experiencing allergy symptoms.
Elmira Police welcomes new officer to the department
ELMIRA, N.Y. (WENY) -- The Elmira Police Department welcomed a new officer into the department on Tuesday, August 1st, swearing in Abdallah Hassan. A graduate of the Spring, 2022 session of the Southern Tier Law Enforcement Academy, Hassan previously worked at the Ithaca College Office of Public Safety and Emergency Management. Officer Hassan is now set to enter the Elmira Police Department Field Training Program to get a feel for serving in the department.
Public invited to burial of nun with ties to Elmira
ELMIRA, N.Y. (WENY) -- The public has been invited to the burial of Sister Arlene Semesky in Elmira next Monday after she died earlier this month in a car crash near Erie, Pennsylvania. A joint funeral is scheduled for Semesky and Sister Joanne Deck, who died as a result of injuries she sustained in the same car crash that killed Semesky. The funeral mass for the two nuns, who were both Sisters of Mercy, is scheduled for Saturday, August 5th at 10 a.m. in the chapel at Mercy Center in Rochester.
Schuyler County to part ways with Co. Administrator after less then two years
WATKINS GLEN, N.Y. (WENY) -- Roughly two weeks after being placed on paid administrative leave for unknown reasons, Schuyler County Administrator Fonda Chronis's last day will be Friday, July 28th. According to County Attorney Steven Getman, the move was a mutual decision. "I am thankful for the trust placed in me and the opportunity to serve.
Tioga Co., Pa man charged with sexual abuse of children
NELSON TOWNSHIP, PA (WENY) -- A 52-year-old man from Tioga County, Pennsylvania has been charged with multiple counts of sexually abusing children. Timothy Lee Gardner was arrested after police say they served a warrant on his home in Nelson Township and discovered multiple devices with images of child porn. Located on the 8000 area of Route 49 in Nelson Township, police say they learned an email address, trading what police termed as "illegal files", was linked to the address.
Ithaca man charged with murdering his father
ITHACA, N.Y. (WENY) -- A 28-year-old man from Ithaca has been charged with murdering his father. Police initially responded to reports of a suspicious death in the 1000 block of Danby Rd. in the Town of Ithaca on July 19th after initially responding to what was called a domestic incident. After investigating, Keith Rowser Jr. was arrested and charged with second degree murder for allegedly killing his father, 52-year-old Keith Rowser Sr., also of Ithaca.
Hornell gets millions to replace Church St. Bridge
HORNELL, N.Y. (WENY) -- The City of Hornell announced on Tuesday, July 18th that it is set to get $2.928 Million in state funding to replace the bridge on Church Street that runs over Canacadea Creek. Part of roughly $53 million of BridgeNY funds being spent in the Southern Tier, the program is designed to replace local bridges and culverts.
Police ask for public's help after road rage attack in Ithaca
ITHACA, N.Y. (WENY) -- Police are asking for the public's help finding a man they say assaulted a pregnant woman in the parking lot of a Dunkin Donuts after an alleged road rage incident in the Town of Ithaca. According to the Tompkins County Sheriffs Office, 25-year-old Anthony Cruz has a warrant out for criminal mischief and assault.
Addison man dead after motorcycle crash in Pa.
TIOGA COUNTY, PA (WENY) -- A 74-year-old Addison man is dead after he crashed his Harley Davidson Fat Boy on Route 6 in Delmar Township, Pennsylvania on Sunday, July 16th. Pennsylvania State Police say Alan Freeman was injured after being thrown from his bike after it struck a guardrail. Freeman was declared dead after being transported to Soldiers and Sailors Memorial Hospital. The motorcycle was the only vehicle involved in the crash.
Broome Co. middle school principal accused of attempted rape out on bail
(Daniel Erickson's photo from the Johnson City Central School District website) BROOME COUNTY, N.Y. (WENY) -- The Johnson City Central School District middle school principal who was charged with trying to rape a 16-year-old girl was bailed out of Chemung County Jail by his wife. That's according to officials from the Broome County Court, who say 55-year-old Daniel Erickson is now free on $5,000 bail.
Schuyler County places Co. Administrator on leave
WATKINS GLEN, N.Y. (WENY) -- WENY News has confirmed with the Schuyler County Legislature that it has placed County Administrator Fonda Chronis on Administrative Leave. County officials would not comment on the reason why, or how long the leave is expected to last.
Bradford County set for 22nd Senior Expo on July 21st
BRADFORD COUNTY, PA (WENY) -- The Lynch-Bustin Elementary School in Athens is set to host the 22nd Bradford County Senior Expo on Friday July 21st. Hosted by Pennsylvania State Rep. Tina Picket (R-Bradford), and will include a town hall meeting with a state officials on how to prevent identity theft.
Fatal crash in Bradford County
It is currently unknown how many vehicles or people were involved. Emergency crews were on on the scene in the early morning hours of Thursday, July 6th.
Ithaca man arrested after high speed chase ends in Campbell
CAMPBELL, N.Y. (WENY) -- A 25-year-old Ithaca man is in custody after police say he led multiple departments on a high speed chase on Thursday, June 29th, while keeping his passenger in the car against their will. Massia White-Saunders faces a myriad of charges, including reckless endangerment, Criminal Possession of Stolen Property, Unlawful Imprisonment and Unlawfully Fleeing a Police Officer amongst others.
Three Newfield men arrested on kidnapping and robbery charges
VAN ETTEN, N.Y. (WENY) -- New York State Police say they have arrested three men from Newfield for robbing a Van Etten man at gunpoint before abducting him in February. Joseph Howell, 37, David Maycumber, 41, and Michael P. Inman, 46, have been charged with Robbery 1st, a B Felony, and Kidnapping 2nd, also a B Felony. According to police the three men stole firearms from the victim before forcing him to a second location at gunpoint.
Fireworks on the 4th of July: When and where in the Twin Tiers
TWIN TIERS (WENY) -- The 4th of July is almost here and for many families throughout the Twin Tiers that means barbeque and fire works. If you don't want to take the risk of setting off fireworks in your backyard, the following is a list of fireworks shows throughout the area. Saturday, July 1: Independence Day Celebration, John J. Collins Park, Galeton, 10 p.m. For more information visit here.
Greenidge Generation: Marking 1 year since the DEC denied its air permit renewal
DRYDEN, N.Y (WENY) -- Roughly a year after Greenidge Generation had its air permit denied by the DEC, opponents and advocates for the crypto-mining operation are still arguing over whether or not it should be closed. Concerned residents and environmental non-profits staged a rally on Wednesday, July28th in Geneva, to keep the pressure on New York State to deny Grennidge's appeal of the permit denial.
Police: man tried to grab deputy's gun after violent home invasion
NEWARK VALLEY, N.Y. (WENY) -- The Tioga County's Sheriff Office out of New York say a 60-year-old man tried to take a deputy's gun after he was pulled over as a suspect of a violent home invasion on Monday, June 19th. Sean Dickenson of Berkshire faces over a dozen charges after police say he broke into a home with a knife and crowbar before making an attempt on a police officer's service weapon.
Town of Ithaca honored with conservation award by Finger Lakes Land Trust
ITHACA, N.Y. (WENY) -- The Town of Ithaca was one of two municipalities to be named Conservationists of the Year by the Finger Lakes Land Trust on Monday, June 26th. Joined by the Town of Canandaigua, Ithaca took home the honor for work to preserve land bordering the Cayuga inlet.
EPD investigating shooting in Southside of Elmira
6/21/2022, 5 p.m. - UPDATE: Elmira Police arrested a 20 year-old-Elmira man in connection with an incident on the Southside of Elmira yesterday when gunfire struck a passing vehicle. Jose Polanco was located in the 300 block area of Broadway street and was arrested without incident. Polanco was charged with criminal posession of a weapon and is being held pending arraignment. A search warrant was executed at the residence where Polanco was located, but the weapon was not recovered.
Proposed travel center in Big Flats could face another hurdle
BIG FLATS, N.Y. (WENY) -- A proposed travel center that would be built adjacent to Sperr Park has engendered a lot of public backlash, and at least one Chemung County Legislator has publicly joined the chorus. Rodney Strange, the legislator for the 15th District has announced that if any part of the travel center comes up for a vote, he will vote no.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Benjamin
Contact Benjamin, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack