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Bingying Zhou

As seen in: Nature, PLOS ONE, MDPI, Cell Press, The Journal of Biological Chemistry, Journal of Molecular and Cellular Cardiology
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Articles

Single-cell transcriptomics uncovers endothelial progenitor-like remodelling driving human coronary atherosclerosis progression

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By Fang Yao, Fangzhou Li, Shujie Gai, Yinan Chen, Fei Liu, Xingzhong Zhang, Jun Li, Lin Mao, Liliang Guo, Kun Xing, Juan Huang, Shufang Fu, Yang Sun, Jinhua Chen, Heng Zhang, YIHAN CHEN, Bingying Zhou, Li Wang, Zhe Zheng
| Nature Verified
Abstract Coronary atherosclerosis underlies life-threatening conditions such as myocardial infarction and stroke, yet its cellular dynamics remain incompletely understood. Here, through single-cell RNA sequencing of 27,941 cells from 56 human coronary segments, we constructed a disease-stage-resolved cellular atlas, revealing pathological remodelling of endothelial cells (ECs) into a progenitor-like state (EC5SLCO4A1+) with low expression of canonical EC dysfunction signatures.
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Mitochondrial Dysfunction in Cardiac Diseases and Therapeutic Strategies

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By Yafei Huang, Bingying Zhou
| ncbi.nlm.nih.gov
Save citation to file Format: Add to My Bibliography Your saved search Name of saved search: Search terms: Frequency: Which day? Which day? Report format: Send at most: Send even when there aren't any new results Optional text in email: Create a file for external citation management software
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Mitochondrial Dysfunction in Cardiac Diseases and Therapeutic Strategies

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By Yafei Huang, Bingying Zhou
| MDPI
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessReview by Yafei Huang and Bingying Zhou * State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, 167 North Lishi Road, Xicheng District, Beijing 100037, China * Author to whom correspondence should be addressed.
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