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Blake M Hauser on Muck Rack

Blake M Hauser

As seen in: Nature, Sexually Transmitted Infections, BioRxiv, Cell Reports, Cell Press, Cell Reports Medicine, Healio
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Articles

Recent vaccination exposure and central serous chorioretinopathy

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By Maria Anna Bantounou, Dimitra Foteinou, Maria Emfietzoglou, Konstantinos G. Baroutis, Blake M Hauser, Petros Petrou, Elizabeth J. Rossin, Joan Miller, Demetrios Vavvas
| Nature Verified
Abstract Central serous chorioretinopathy (CSCR) is characterised by choroidal hyperpermeability and potential dysregulation of inflammatory cytokines. Because vaccination transiently activates cytokine pathways, we assessed whether vaccination is associated with incident CSCR. We performed a case–control study in the Mass General Brigham database among adults 18–60 years.
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Structure-based network analysis predicts pathogenic variants in human proteins associated with inherited retinal disease - npj Genomic Medicine

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By Blake M Hauser, Demetrios Vavvas, Kinga M. Bujakowska, Gaurav D. Gaiha
| Nature Verified
Abstract Advances in gene sequencing technologies have accelerated the identification of genetic variants, but better tools are needed to understand which are causal of disease. This would be particularly useful in fields where gene therapy is a potential therapeutic modality for a disease-causing variant such as inherited retinal disease (IRD).
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Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds - Nature Communications

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By Larance Ronsard, Grant A. Knappe, Blake M Hauser, Anna Romanov, James Case, Julie Boucau, Amy K. Barczak, Alejandro B Balazs, Michael Diamond Verified, Aaron Schmidt Verified, Daniel Lingwood
| Nature Verified
Abstract Protein-based virus-like particles (P-VLPs) are commonly used to spatially organize antigens and enhance humoral immunity through multivalent antigen display. However, P-VLPs are thymus-dependent antigens that are themselves immunogenic and can induce B cell responses that may neutralize the platform.
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