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Articles by Bowei Yang
Antioxidant lipid nanoparticles enhance mRNA stability for regeneration therapy and gene editing
Abstract The success of mRNA vaccines has motivated the development of mRNA therapeutics to treat a wide range of diseases, as well as applications in regenerative medicine. However, the inherent instability of mRNA under conditions of oxidative stress renders these applications challenging. Here we report a general approach to shield mRNA from oxidative degradation by incorporating antioxidant lipid within lipid nanoparticles (LNPs).
Neutrophil-hitchhiking nanoplatform overcomes blood–brain barrier to treat cerebral ischemia-reperfusion injury via ferroptosis inhibition and microglial modulation
Abstract Cerebral ischemia reperfusion injury (CIRI) after stroke is hard to treat because the blood–brain barrier (BBB) blocks most drugs, while reperfusion triggers oxidative stress, ferroptosis, and neuroinflammation. We designed a neutrophil hitchhiking lipid nanoparticle (RKH Neu@Mino) by conjugating an RKH peptide (from Akkermansia muciniphila) onto DSPE PEG maleimide and encapsulating minocycline via microfluidic assembly.
Rational design of rigid mRNA folding architecture to enhance intracellular processing and protein production - Nature Nanotechnology
Abstract The application of messenger RNA (mRNA) beyond infectious diseases is challenged by inefficient protein production. Whereas the engineering of secondary mRNA structures has been shown to increase mRNA half-life, it remains unclear whether tertiary mRNA structures influence therapeutic efficacy.
STING‐Activating Polymers Boost Lymphatic Delivery of mRNA Vaccine to Potentiate Cancer Immunotherapy (Adv. Mater. 10/2025)
Xiaoyuan Chen Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119074 Singapore Nanomedicine Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597 Singapore Department of Chemical and Biomolecular Engineering, and Department of Biomedical Engineering, College of Design and Engineering, National University of Singapore, Singapore, 119074 Singapore Department of...
Research on the Effects of the Water-Binder Ratio and Fiber Content on the Tensile and Bending Mechanical Properties of ECCs
1. Introduction Engineered cementitious composites (ECCs) are high-ductility, fiber-reinforced cementitious composites pioneered and designed by Li V C. of the University of Michigan, USA [1,2,3,4].
Microstructure and Tensile Property Tailoring of Al-5Mg (wt%) Alloy Combined with Continuous Rheo-Extrusion and Sc Modification
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Fault-Tolerant Control for Multi-UAV Exploration System via Reinforcement Learning Algorithm
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Sustainability | Free Full-Text | Experimental Study on the Durability Performance of Sustainable Mortar with Partial Replacement of Natural Aggregates by Fiber-Reinforced Agricultural Waste Walnut Shells
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Synergistic Glutathione Depletion and STING Activation to Potentiate Dendritic Cell Maturation and Cancer Vaccine Efficacy
Conflict of interest The authors declare no conflict of interest. Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Optimisation of the Mechanical Properties and Mix Proportion of Multiscale-Fibre-Reinforced Engineered Cementitious Composites
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by 1, 1,2, 1,3, 1 and 1,* 1 College of Civil Engineering, Architecture and Environment, Hubei University of Technology, Wuhan 430068, China 2 China Construction Seventh Engineering Division Co., Ltd., Zhengzhou 450003, China 3 China Construction Third Engineering Bureau (Shenzhen) Co., Ltd., Shenzhen 518000, China * Author to whom correspondence should be addressed.
Optimal Design of Multi-Scale Fibre-Reinforced Cement-Matrix Composites Based on an Orthogonal Experimental Design
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Polarization-Dependent Absorption and Transmission Metasurfaces for Linearly and Circularly Polarized Light in Terahertz Band
Open AccessArticle by Bowei Yang 1, Mingzhao Ouyang 1,2,3, Hang Ren 1,2,3, Jinshuang Wu 1, Yixin Zhang 4 and Yuegang Fu 1,2,3,* 1 School of Optoelectronic Engineering, Changchun University of Science and Technology, Changchun 130022, China 2 Key Laboratory of Optoelectronic Measurement and Optical Information Transmission Technology of Ministry of Education, Changchun University of Science and Technology, Changchun 130022, China 3 Key Laboratory of Advanced Optical System Design and...
Sentiments and Sorrows
Brimming with emotion, Bowei Yang’s portraits create a space of healing in which the photographer and his subjects can explore their identities, liberating themselves from their conservative backgrounds. Chinese photographer Bowei Yang grew up in a traditional Christian family in a small and picturesque town on the Fuchun River in southern China. It was an intensely religious upbringing, he says, and one he struggled with as he tried to find his own identity.
Facile fabrication of shell crosslinked microcapsule by visible light induced graft polymerization for enzyme encapsulation
Facile fabrication of shell crosslinked microcapsule by visible light induced graft polymerization for enzyme encapsulation† Kai Zhang,ab Guangjun Shao,ab Bowei Yang,ab Changwen Zhao, *ab Yuhong Ma c and Wantai Yang*abd Author affiliations * Corresponding authors a State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China E-mail: zhaocw@mail.buct.edu.cn, yangwt@mail.buct.edu.cn b Beijing Laboratory of Biomedical Materials, Key...
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