Brenna M. Henn on Muck Rack

Brenna M. Henn

  • Associate Professor of Anthropology, University of California, Davis
As seen in: Nature, The Conversation, Genome Biology, Independent Online, Cell Press, Arizona Daily Star, AllAfrica, Omaha World-Herald, Richmond Times-Dispatch, Buffalo News and
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Articles

Challenges and recommendations in establishing national human diversity genomic projects

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By Taras Oleksyk, Walter Wolfsberger, Karishma Chhugani, Yu-Ning Huang, Valerii Pokrytiuk, Khrystyna Shchubelka, Alex Zelikovsky, Bogdan Pasaniuc, Viorel Jinga, Octavian Bucur, Scott Edmunds, Heinner Guio, Zané Lombard, Brenna M. Henn, Andrei Lobiuc, Dumitru Ciorba, Viorel Bostan, Viorel Munteanu, Victor Gordeev, Christian Schaaf, Boon-Peng Hoh, Andrés Estrada Verified, Mihai Covasa, Mihai Dimian, Ulykbek Kairov, Victoria M. Pak, Charleston W. K. Chiang, Matteo Pellegrini, Yosr Hamdi, Malak Abedalthagafi, Nicola Mulder, Jazlyn Mooney, Javier E. Sanchez-Galan, Henriette Raventós, Marina Muzzio, Gabriela Chavarria-Soley, Serghei Mangul, Alexei Levitchi, Emmanuel Nepolo, Sandro José de Souza
| Nature Verified
To ensure that the benefits of biomedical research are shared globally, we must overcome the barriers preventing the establishment of national genomic projects in underrepresented regions by navigating the ethical, legal and financial complexities of launching these initiatives.
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Recurrent structural variation and recent turnover at the 17q21.31 locus in humans and great apes

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By Samvardhini Sridharan, Runyang Nicolas Lou, Scott Ferguson, Joana Rocha, Rishi De-Kayne, Matthew Mitchell, Brenna M. Henn, Peter H. Sudmant, Alison N. Killilia
| Nature Verified
Abstract The 17q21.31 locus in humans harbors several complex structural haplotypes including a ~ 970 kb inversion. Different inversion haplotypes have been associated with susceptibility to microdeletions causing Koolen-de Vries syndrome and variation in fecundity and recombination rates. Here, using 210 haplotype-resolved human genome assemblies and pangenome graph-based approaches we characterize 11 distinct structural haplotypes, several of which have not been previously described.
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Common DNA sequence variation influences epigenetic aging in African populations - Communications Biology

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By Gillian Meeks, Sean P. Prall, Etienne Patin, Maud Fagny, Brenna M. Henn
| Nature Verified
Abstract Aging is associated with genome-wide changes in DNA methylation in humans, facilitating the development of epigenetic age prediction models. However, these models have been trained primarily on European-ancestry individuals and none account for the impact of methylation quantitative trait loci (meQTL).
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