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Carolyne Bardeleben on Muck Rack

Carolyne Bardeleben

As seen in: Cell Reports
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Signaling bias of the protease-activated receptor-1 is dictated by distinct GRK5 and β-arrestin-2 determinants

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By Mónica Ramírez Verified, Huaping Qin, Ying Lin, Cierra A. Birch, Irina Kufareva, JoAnn Trejo, Lennis B. Orduña-Castillo, Carolyne Bardeleben
| Cell Reports Verified
Keywords APC activated protein C biased agonists biased signaling G protein GPCR G protein-coupled receptor GRK G protein-coupled receptor kinase PAR1 phosphorylation thrombin Research topic(s) CP: molecular biology Introduction G protein-coupled receptors (GPCRs) transduce signals in response to a wide range of stimuli, modulate most physiological functions, and are highly druggable.
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