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Charles Brenner on Muck Rack

Charles Brenner

Iowa City
As seen in: Nature, Wiley Online Library, Scientific American, Science Magazine, Cell Metabolism, Cell Press, MindBodyGreen, Healio, City of Hope, South Florida Reporter and
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Articles

Nordic track: NIH dysfunction and my Helsinki recruitment

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By Charles Brenner
| Cell Press Verified
Affiliations & Notes 1Department of Diabetes and Cancer Metabolism, Beckman Research Institute, Duarte, CA, USA 2Sustainable Wellbeing Across Lifespan, Faculties of Medicine and Pharmacy and the Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland Article Info Publication History: Published online July 8, 2026 DOI: 10.1016/j.tem.2026.06.003 External LinkAlso available on ScienceDirect External Link Copyright: © 2026 Elsevier Ltd.
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Metabolic profiling reveals pyrimidine synthesis enzyme CAD as a central carbon metabolism signaling node in cancer cell proliferation

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By Chao Qin, Zhenhao An, Shu Feng, Xinchi Xie, Ali Can Savas, Taolin Xie, Charles Brenner, Takeshi Saito, Pinghui Feng
| Cell Press Verified
Keywords Cancer metabolism deamidation pyrimidine synthesis CAD the pentose phosphate pathway the serine synthesis pathway G6PD PHGDH central carbon metabolism Get full text access Log in, subscribe or purchase for full access. References 1. Feitelson, M.A. ∙ Arzumanyan, A. ∙ Kulathinal, R.J. ... Sustained proliferation in cancer: Mechanisms and novel therapeutic targets Semin. Cancer Biol. 2015; 35:S25-S54 2. Evan, G.I. ∙ Vousden, K.H. Proliferation, cell cycle and apoptosis in cancer Nature.
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The NARly side of whole-body NAD homeostasis

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By Charles Brenner
| Cell Metabolism Verified
Get full text access Log in, subscribe or purchase for full access. References 1. Belenky, P. ∙ Bogan, K.L. ∙ Brenner, C. NAD+ metabolism in health and disease Trends Biochem. Sci. 2007; 32:12-19 2. Bender, D.A. ∙ Magboul, B.I. ∙ Wynick, D. Probable mechanisms of regulation of the utilization of dietary tryptophan, nicotinamide and nicotinic acid as precursors of nicotinamide nucleotides in the rat Br. J. Nutr. 1982; 48:119-127 3. Trammell, S.A.J. ∙ Schmidt, M.S. ∙ Weidemann, B.J. ...
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