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Chen-Long Li on Muck Rack

Chen-Long Li

As seen in: Nature, Wiley Online Library, arXiv, Royal Society of Chemistry, Physical Review B, Optica, Chemistry World, Aging, ENTtoday
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Articles

Sequence Display enables large-scale sequence–activity datasets for rapid protein evolution

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By Linqi Cheng, Xinzhe Zheng, Shiyu Jiang, YU HU, Yijie Liu, Kaiqiang Yang, Jinyan Rui, Mengxi Zhang, Teng Yuan, Qianglan Lu, Haoxin Ye, Chen-Long Li, Yiming Guo, Anna Qin, Boyang Zhou, Kevin Yang, Xiongyi Huang, Han Xiao, Haoxue Ding, Zuotong Tian
| Nature Verified
Abstract Engineering proteins with desired functions remains challenging and usually requires multiple rounds of screening and selection. Here, we present Sequence Display, a platform that generates large-scale protein sequence–activity datasets in a single round. Sequence Display enables multiplexed assessment of individual variant activity within a single experiment, offering a robust approach to mapping detailed sequence–function relationships.
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Ynamide Protonation-Initiated N-Heteropolyene Cyclization

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By Han Chen, Chen-Long Li, Can Liu, Zhenjia Zhang
| dx.doi.org
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How To: Quantitative Framework Fabrication with Autogenous Costal Cartilage in Microtia Reconstruction

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By Chen-Long Li, You-Zhou Xie, Aijuan He, Ning-Hua Liu, Chun-Xiao Cui, Ying Chen, Yaoyao Fu, Tianyu Zhang
| ENTtoday
Microtia is mainly characterized by hypoplasia of the auricle, external auditory canal, and middle ear. It usually affects both appearance and hearing. The core of microtia reconstruction is framework fabrication, and an exquisite framework can increase the satisfaction rate and meet the natural aesthetic requirements. (Plast Reconstr Surg. 2014;133(5):1168-1174). In this article, we presented a quantitative framework fabrication technique which mainly needs three rib cartilages.
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