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Articles by Chen Su
Satellite glial cell remodeling associated with IL-6-associated Fas–FasL signaling contributes to chronic neuropathic pain after nerve injury
Abstract Neuropathic pain after peripheral nerve injury is associated with sustained remodeling of the dorsal root ganglion (DRG) microenvironment. Although the neuronal mechanisms have been extensively studied, how neuron–glia–immune interactions contribute to chronic pain maintenance remains unclear. We investigated whether persistent interleukin-6 (IL-6) signaling is linked to Fas–Fas ligand (FasL)-associated satellite glial cell (SGC) remodeling during chronic neuropathic pain.
“Resembling a policeman conducting traffic”: the Peace Statue in A Pale View of Hills
Advanced search The Explicator Latest Articles Submit an article Journal homepage Full Article Figures & data References Citations Metrics Reprints & Permissions Read this article /doi/full/10.1080/00144940.2026.2722203?needAccess=true Click to increase image sizeClick to decrease image size Disclosure statement No potential conflict of interest was reported by the author(s).
ABLIM1 supports cerebrovascular endothelial barrier integrity in an IL-1β-treated hCMEC/D3 model
Abstract In Alzheimer’s disease (AD), the role of Actin-binding LIM protein 1 (ABLIM1), which is highly enriched in the brain endothelium, in blood-brain barrier (BBB) dysfunction remains unclear. Our integrative multi-omics analysis, integrating single-cell transcriptomics from AD patient cerebrovascular endothelial cells, transcriptomics from animal models, and vascular endothelial proteomics, identified ABLIM1 as the only overlapping gene across three datasets.
A thermoregulatory module for timekeeping in Arabidopsis
Keywords phyB PRR9 circadian clock m6A thermal adaptation high temperature Get full text access Log in, subscribe or purchase for full access. References 1. Bohn, L. ∙ Huang, J. ∙ Weidig, S. ... The temperature sensor TWA1 is required for thermotolerance in Arabidopsis Nature. 2024; 629:1126-1132 2. Chung, B.Y.W. ∙ Balcerowicz, M. ∙ Di Antonio, M. ... An RNA thermoswitch regulates daytime growth in Arabidopsis Nat. Plants. 2020; 6:522-532 3. Jung, J.H. ∙ Barbosa, A.D. ∙ Hutin, S. ...
NVIDIA Introduces New Jetson Thor Computers to Advance Mainstream Robotics and Edge AI
General-purpose robots and autonomous machines are moving from research labs to real-world mass-market deployment, creating demand for compact, power-efficient AI supercomputers capable of running foundation models at the edge. To meet that need, NVIDIA today introduced the T3000 and T2000, new modules based on the NVIDIA Thor architecture that enable mass-market robotics and edge AI applications at scale.
Firefly Aerospace operates NVIDIA Jetson in Lunar orbit for the first time
The NVIDIA Inception member’s Ocula moon imaging service will harness the NVIDIA Jetson platform for edge AI, running inference directly in space to significantly accelerate insights compared with downlinking all data back down to Earth By Chen Su, Nvidia When Firefly Aerospace’s Blue Ghost Mission 1 landed on the moon in March 2025, the lander downlinked nearly 120 gigabytes of raw data back to Earth — imagery and video captured by onboard cameras that scientists are still processing today.
Firefly Aerospace Operates NVIDIA Jetson in Lunar Orbit for the First Time
The NVIDIA Inception member’s Ocula moon imaging service will harness the NVIDIA Jetson platform for edge AI, running inference directly in space to significantly accelerate insights compared with downlinking all data back down to Earth. When Firefly Aerospace’s Blue Ghost Mission 1 landed on the moon in March 2025, the lander downlinked nearly 120 gigabytes of raw data back to Earth — imagery and video captured by onboard cameras that scientists are still processing today.
LysePred: A Multiscale Convolutional Neural Network for Predicting Hemolytic Activity of Antimicrobial Peptides Click to copy article link Article link copied!
Abstract Click to copy section linkSection link copied! Antimicrobial peptides (AMPs) represent promising alternatives to conventional antibiotics, yet hemolytic toxicity remains a critical barrier to clinical translation, with approximately 70% of known AMPs exhibiting high or moderate hemolytic activity.
NVIDIA Jetson Brings Agentic AI to the Physical World
Agentic AI is getting physical. At COMPUTEX on Tuesday, NVIDIA announced NVIDIA JetPack 7.2 and NVIDIA NemoClaw support on NVIDIA Jetson. JetPack 7.2 brings agentic AI skills, Yocto project support, NVIDIA CUDA 13 on NVIDIA Jetson Orin, a substantial performance gain on Jetson AGX Orin 32GB module and Multi-Instance GPU (MIG) support on NVIDIA Jetson Thor. NVIDIA’s Asier Arrnaz shows how Build-a-Claw brings AI to the edge, a personalized, always-on assistant running right on NVIDIA Jetson.
Compression-induced metabolic adaptation drives confined tumor cell migration and distant metastasis via malate-dependent microtubule reinforcement
Abstact Metastasis, responsible for > 90% of cancer-related mortality, represents the most lethal yet least mechanistically understood phase of cancer progression. A critical bottleneck is tumor cell migration through physically confined environments, including dense extracellular matrix, narrow capillaries and endothelial gaps.
Effects of cumulative systolic blood pressure on arterial stiffness: a cross-sectional study based on a community in northern China with 16 years of follow-up
Abstract To determine the impact of cumulative systolic blood pressure (cumulative SBP) on increased arterial stiffness in a northern Chinese community. A total of 427 participants from the Kailuan study were enrolled. The median age was 59.0 years (interquartile range 52.0, 66.0). Cumulative SBP was calculated from BP measurements recorded in 2006–2022 by quartile. Logistic regression was used to estimate odds ratios (ORs) and confidence intervals (CIs).
eGFR- and Potassium-Guided Stewardship of SGLT2 Inhibitors and Finerenone in Albuminuric Chronic Kidney Disease Associated with Type 2 Diabetes
Back to Journals » Diabetes, Metabolic Syndrome and Obesity » Volume 19 Review Diabetes Pathophysiology and Complications Authors Su C, Li X, Wang S, Liu D Received 4 May 2026 Accepted for publication 25 August 2026 Published 10 September 2026 Volume 2026:19 621958 DOI https://doi.org/10.2147/DMSO.S621958 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Dr Rebecca Baqiyyah Conway Chen Su,1,* Xumin Li,2,* Shuang...
As Open Models Spark AI Boom, NVIDIA Jetson Brings It to Life at the Edge
The Cat 306 CR mini-excavator weighs just under eight tons and fits inside a standard shipping container. It’s the machine a contractor rents when the job site is tight: a utility trench near a foundation, a basement dig in a dense neighborhood. The cab is roughly the size of a phone booth. The operator sits close to the controls, two joysticks, multiple functions per hand. It takes time to learn. It takes longer to speed up.
Inhibiting Mrt4-rRNA interaction with fumaramidmycin-based derivatives as an antifungal strategy - Nature Communications
Abstract The rise of drug resistance and limitations of current antifungal treatments highlight the urgent need for innovative antifungal strategies. Here we present the development of cis-fumaramidmycin-derived analogs inhibiting the interactions of ribosome assembly factor Mrt4 with rRNA to combat fungal infections. Through antifungal screening, we identified a promising lead 20 with strong efficacy against various drug-resistant fungi, including notorious super-fungus Candida auris.
SFRT alleviates symptoms associated with bulky advanced cancer: a retrospective single-center cohort analysis
Abstract Objective/background: To evaluate the impact of Spatially Fractionated Radiation Therapy (SFRT) on symptomatic relief and survival outcomes in patients with large-volume tumors. Methods: A total of 60 cancer patients who received SFRT between February 2023 and May 2025 were analyzed in this retrospective study.
Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis
1 Introduction Autoimmune hepatitis (AIH) is a severe immune-mediated liver disease characterized by progressive necroinflammatory damage, immune cell activation, and infiltration [1]. Despite a rising incidence worldwide, the precise pathogenesis of AIH remains incompletely elucidated [2].
Gerotranscendence reflected in Iris Murdoch’s The Sea, The Sea
ABSTRACT This paper explores the theme of self-transcendence in Iris Murdoch’s The Sea, The Sea, offering a fresh perspective on aging as a journey of moral and spiritual growth. By examining the character of Charles Arrowby through the lens of literary gerontology and philosophical ethics, the paper brings together Murdoch’s portrayal of later life with theories of transcendence in gerontological studies.
GI‐ScreenNet v2: A Modular Framework for Gastrointestinal Disease Detection Based on an Integrated Transfer Learning
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The KvasirV2 dataset used in this study is a publicly available benchmark dataset. All data supporting the findings of this study are referenced in the article. References 1 World Health Organization, Global Health Estimates: Leading Causes of Death (WHO, 2023). 2, , , and , “Wireless Capsule Endoscopy,” Nature 405, no. 6785 (2000): 417, https://doi.org/10.1038/35013140.
Robots’ Holiday Wishes Come True: NVIDIA Jetson Platform Offers High-Performance Edge AI at Festive Prices
Editor’s note: This blog has been updated to showcase additional recent innovations tapping into the NVIDIA Jetson platform. Developers, researchers, hobbyists and students can take a byte out of holiday shopping this season as NVIDIA has unwrapped special discounts on the NVIDIA Jetson family of developer kits for edge AI and robotics — available through Sunday, Jan. 11.
Impact of MEK inhibition on T-cell infiltration and function after radiotherapy in KRAS-mutant lung cancer
ORIGINAL RESEARCH article Volume 16 - 2025 | https://doi.org/10.3389/fimmu.2025.1663502 This article is part of the Research TopicCancer Immunity, Modern Radiotherapy and Immunotherapy: A Journey into Cancer Treatment InnovationView all 10 articles 1 Introduction Ki-ras2 (KRAS) mutations serve as driver genes in non-small cell lung cancer (NSCLC), with approximately 27% incidence among Caucasians (1) and 9% among Chinese (2).
Halogen Co‐Mixing-An Effective Strategy for Optimizing Luminescent Performance of Copper‐Based Hybrid Scintillator
Conflict of Interests The authors declare no conflict of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description anie70308-sup-0001-SuppMat.docx5.6 MB Supporting Information References 1, , , , , , , , , , , , , Nat. Biomed. Eng. 2023, 7, 1242–1251, https://doi.org/10.1038/s41551-023-01024-2. 2, , , , , , , , , , , , , , , , , , , , , , , , , , , , Nat. Commun.
NVIDIA IGX Thor Robotics Processor Brings Real-Time Physical AI to the Industrial and Medical Edge
AI is moving from the digital world into the physical one. Across factory floors and operating rooms, machines are evolving into collaborators that can see, sense and make decisions in real time. To accelerate this transformation, NVIDIA today unveiled NVIDIA IGX Thor, a powerful, industrial-grade platform built to bring real-time physical AI directly to the edge, combining high-speed sensor processing, enterprise-grade reliability and functional safety in a small module for the desktop.
A circadian morning complex modulates far-red light signaling in Arabidopsis - Nature Communications
Abstract The plant circadian clock coordinates internal processes with daily and seasonal environmental changes by interacting with prevalent light cues. However, how the circadian clock feedback regulates light signals remains largely elusive.
NVIDIA Jetson Thor Unlocks Real-Time Reasoning for General Robotics and Physical AI
Robots around the world are about to get a lot smarter as physical AI developers plug in NVIDIA Jetson Thor modules — new robotics computers that can serve as the brains for robotic systems across research and industry. Robots demand rich sensor data and low-latency AI processing. Running real-time robotic applications requires significant AI compute and memory to handle concurrent data streams from multiple sensors.
Purification-Free Bortezomib-Drug Conjugates Optimize Drug Economy and Cancer Therapeutic Synergy
Biological and Medical Applications of Materials and InterfacesApril 9, 2025 Meng Li Department of Radiopharmaceuticals, School of Pharmacy, Nanjing Medical University, Nanjing 211166, P. R. China NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, P. R. China Wei Wu Department of Radiopharmaceuticals, School of Pharmacy, Nanjing Medical University, Nanjing 211166, P. R.
Development of a Modular Design and Detachable Mechanism for Safety Support Products in Winter Ice Fishing
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Prevalence and correlation of sarcopenia with Alzheimer’s disease: A systematic review and meta-analysis
Loading metrics Open Access Peer-reviewed Research Article Citation: Su C, Zhang S, Zheng Q, Miao J, Guo J (2025) Prevalence and correlation of sarcopenia with Alzheimer’s disease: A systematic review and meta-analysis. PLoS ONE 20(3): e0318920. https://doi.org/10.1371/journal.pone.0318920 Editor: Francesco Curcio,, University of Naples Federico II, ITALY Received: August 30, 2024; Accepted: January 23, 2025; Published: March 3, 2025 Copyright: © 2025 Su et al.
A High-Speed Finger Vein Recognition Network with Multi-Scale Convolutional Attention
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Multifunctional Dual Crosslinked Ti₃C₂Tx MXene Based Hydrogels for Wearable Sensors with Enhanced Mechanical Robustness and Broadband Microwave Absorption
Multifunctional Dual Crosslinked Ti₃C₂Tx MXene Based Hydrogels for Wearable Sensors with Enhanced Mechanical Robustness and Broadband Microwave Absorption The development of multifunctional hydrogels with enhanced mechanical, electrical, and electromagnetic properties has become a key focus in various advanced applications, including wearable electronics, strain sensors, and electromagnetic interference (EMI) shielding.
NVIDIA JetPack 6.2 Brings Super Mode to NVIDIA Jetson Orin Nano and Jetson Orin NX Modules
The introduction of the NVIDIA Jetson Orin Nano Super Developer Kit sparked a new age of generative AI for small edge devices. The new Super Mode delivered an unprecedented generative AI performance boost of up to 1.7x on the developer kit, making it the most affordable generative AI supercomputer. JetPack 6.2 is now available to support Super Mode for Jetson Orin Nano and Jetson Orin NX production modules, delivering up to 2x higher generative AI model performance.
NVIDIA Unveils Its Most Affordable Generative AI Supercomputer
NVIDIA is taking the wraps off a new compact generative AI supercomputer, offering increased performance at a lower price with a software upgrade. The new NVIDIA Jetson Orin Nano Super Developer Kit, which fits in the palm of a hand, provides everyone from commercial AI developers to hobbyists and students, gains in generative AI capabilities and performance. And the price is now $249, down from $499.
India’s Robotics Ecosystem Adopts NVIDIA Isaac and Omniverse to Build Next Wave of Physical AI
In vast warehouses, Addverb’s robots work tirelessly, picking, sorting and delivering products with precision. Across frozen Oslo, Norway, Ottonomy’s Yeti robots assist in navigating icy streets as part of a trial with Posten Norge for urban deliveries, while in sun-soaked Madrid, they autonomously cruise bustling avenues, supporting last-mile delivery services.
CD5L associates with IgM via the J chain - Nature Communications
Abstract CD5 antigen-like (CD5L), also known as Spα or AIM (Apoptosis inhibitor of macrophage), emerges as an integral component of serum immunoglobulin M (IgM). However, the molecular mechanism underlying the interaction between IgM and CD5L has remained elusive. In this study, we present a cryo-electron microscopy structure of the human IgM pentamer core in complex with CD5L.
Innovative Green Synthesis of Hydrophobic Covalent Networks Using Ethyl Cellulose/Thymol Eutectic Systems
Innovative Green Synthesis of Hydrophobic Covalent Networks Using Ethyl Cellulose/Thymol Eutectic Systems Cellulose and its derivatives have shown significant potential as plastic replacement materials due to their outstanding properties. However, current research still faces challenges related to green synthesis, structural design, and multifunctionality.
IJMS | Free Full-Text | The Enhancement Origin of Antioxidant Property of Carboxylated Lignin Isolated from Herbaceous Biomass Using the Maleic Acid Hydrotropic Fractionation
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Correction: Development of a prognostic model for early-stage gastric cancer-related DNA methylation-driven genes and analysis of immune landscape
CORRECTION article Volume 12 - 2025 | https://doi.org/10.3389/fmolb.2025.1658908 In the Funding statement, the name of one of the funders was incorrectly provided as Foundation of Xiamen Municipal Bureau of Science and Technology. The correct funder is Natural Science Foundation of Xiamen, China. An incorrect number was provided for the Natural Science Foundation of Fujian Province. The correct number is No. 2023J011600. The original article has been updated.
An Innovative Method Based on Wavelet Analysis for Chipless RFID Tag Detection
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Copper Iodide Hybrid with Unique Cu3I3 Trimeric Inorganic Functional Unit and Far‐red/Near‐infrared Emission
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Production-Ready, Enterprise-Grade Software on NVIDIA IGX Platform, Support for NVIDIA RTX 6000 ADA, and More
Real-time AI at the edge is crucial for medical, industrial, and scientific computing because these mission-critical applications require immediate data processing, low latency, and high reliability to ensure timely and accurate decision-making. The challenges involve not only high-bandwidth sensor processing and AI computation on the hardware platform but also the need for enterprise-level AI software to support the entire edge computing software stack.
Powering Mission-Critical AI at the Edge with NVIDIA AI Enterprise IGX
NVIDIA SDKs have been instrumental in accelerating AI applications across a spectrum of use cases spanning smart cities, medical, and robotics. However, achieving a production-grade AI solution that can deployed at the edge to support human and machine collaboration safely and securely needs both high-quality hardware and software tailored for enterprise needs. NVIDIA is again accelerating mission-critical AI applications at the edge.
Controllable Dopamine Conjugation Boosts Fluorescence, Biocompatibility, and PET Imaging‐Guided Toxicity Assessment of Polycations
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202400960-sup-0001-SuppMat.pdf2.5 MB Supporting Information References 1a) , , , , , Acc. Chem. Res. 2019, 52, 1347; b) , , , , Prog. Polym. Sci. 2016, 60, 18. 2, , , , , , , , , , , , Nat. Biomed. Eng. 2020, 4, 314. 3a) , , , Nat. Rev. Mater. 2022, 7, 39; b) , Prog. Polym. Sci. 2018, 78, 56; c) , , , , , , , , , , , , , , Sci. Adv. 2022, 8, eabo6406. 4a) , , , , , , , , , , , , , Nat. Nanotechnol.
Strain-tunable half-metallicity in ${\mathrm{VSe}}_{2}/{\mathrm{Sc}}_{2}{\mathrm{CO}}_{2}$ van der Waals heterostructures
The quest for advancing the development of next-generation nanospintronic devices has propelled extensive research into the realization and control of half-metallicity in 2D materials. Here, the multiferroic VSe2/Sc2CO2 vdW heterostructures are theoretically investigated by using density functional theory to search for half-metallicity.
Highly Emissive Organic Antimony Halide with Ferromagnetism and Methanol Sensing Properties
CCDC 2286043 contains the supplementary crystallographic data for this paper. These data can be obtained free of charge via www.ccdc.cam.ac.uk/data_request/cif, or by emailing data_request@ccdc.cam.ac.uk, or by contacting The Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, UK; fax: +44 1223 336033. Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions.
Application of Computed Tomography Scanning Parameters Combined with Serum Cripto-1 in the Diagnosis of Renal Cell Carcinoma
Ning Liu [1] ; Chen Su [2] ; Jianghua Xue [3] [1] Medical Imaging Center, Jinan Central Hospital, Jinan, Shandong, China [2] Oncology Department, Jinan Central Hospital, Jinan, Shandong, China [3] Interventional Department, Jinan Central Hospital, Jinan, Shandong, China Localización: Archivos españoles de urología, ISSN 0004-0614, Tomo 77, Nº. 1, 2024, págs.
J chain dictates the recognition of IgA by FcRL4
Abstract Fc-receptor-like 4 (FcRL4) selectively recognizes systemic IgA. The cryo-electron microscopy structure of the FcRL4-Fca (IgA-Fc)-Joining (J) chain complex reveals that FcRL4 interacts with Fca-J in a 1:1 stoichiometry, with FcRL4 primarily interacting with the J chain. The binding of Fca-J to FcRL4 would hinder the binding of pIgR, but not FcaRI. These findings provide new insights into IgA and emphasize significant differences between various IgA receptors.
CD5L associates with IgM via the J chain
Abstract CD5 antigen-like (CD5L), also known as Spa; or AIM (Apoptosis inhibitor of macrophage), emerges as an integral component of serum immunoglobulin M (IgM). However, the molecular mechanism underlying the interaction between IgM and CD5L has remained elusive. In this study, we present a cryo-electron microscopy structure of the IgM pentamer core in complex with CD5L.
曾憲哲失蹤7日後尋回 據稱停留叢林因有水飲保命
失蹤七天的男拔萃中學生曾憲哲，在沙田小瀝源山上一處叢林尋回，清醒送院。消息指，曾憲哲失蹤期間因為持續落雨，令他衣物濕透很冷，所以脫掉衣物，又指在該處叢林停留，是因為有水喝，得以保命。他的母親就表示，兒子經過風暴及黑雨，仍然在生，形容是神蹟。 消防下午約兩時十五分，在小瀝源老鼠田坑沿溪澗搜索，在附近的叢林找到曾憲哲，他當時神智清醒，但是沒穿衣物。消息指，曾憲哲解釋，由於幾日前下雨，衣物濕掉令他很冷，所以脫掉，又指在該處叢林停留，稱因為有水喝。 消防隊長張天瑜指，大約離開主路徑一百米的位置發現事主，位置接近老鼠田坑水源，又透露，曾經到事主家中，取得其衣物讓搜救犬作氣味鑑別搜索方式，亦用無人飛行器系統拍攝逾一萬張相，利用人工智能(AI)圖像識辨系統，分析這一萬張相片，透過相片收窄搜索範圍。...
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