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Christopher Cherry

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Articles

γδ T cell-stromal networks modulate matrix composition and vascularity in foreign body response

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By Anna Ruta, Kavita Krishnan, Jiwon Woo, Joscelyn C. Mejias, Elise Gray-Gaillard, David R. Jr., Helen Nguyen, Helen Nguyễn, Alexandra Rindone, Christopher Cherry, Michael Patatanian, Frank Yu, Brenda Yang, Connor D. Amelung, Christina King, Birgit Schilling, Sharon Gerecht, Elana Fertig, Locke Davenport Huyer, Drew Pardoll, Jennifer H. Elisseeff
| Nature Verified
Abstract Immune-stromal crosstalk governs tissue fibrosis, which is marked by dysregulated extracellular matrix (ECM) production and aberrant vasculature. Here, we investigate how γδ T cell interactions with stromal cells shape fibrosis in the foreign body response in a murine biomaterial implant model. During the acute reaction, type-1 (γδIFNγ) and type-17 (γδ17) γδ T cell subsets accumulate at the implant site.
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The ‘war’ on disabled people and my fight for an independent life – video | Disability - Business And America

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By Christopher Cherry, Maeve Shearlaw Verified, Kyri Evangelou, Harrison Taylor
| businessandamerica.com
Disability services in the UK have been consistently cut after 14 years of Tory rule and austerity, but with the promise of change from a new Labour government, musician and activist John Kelly is concerned that politicians are still not listening to disabled voices and what they want. Kelly chained himself to London buses in the 1990s to protest over a lack of access to transport, but has watched the right to an independent life be steadily eroded.
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Dysregulation of cellular iron predisposes chemotherapy resistant cancer cells to ferroptosis

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By Luke V Loftus, Louis T.A. Rolle, Christopher Cherry, Michael Patatanian
| biorxiv.org
Abstract Despite centuries of research, metastatic cancer remains incurable due to resistance against all conventional cancer therapeutics. Alternative strategies leveraging non-proliferative vulnerabilities in cancer are required to overcome cancer recurrence. Ferroptosis is an iron dependent cell death pathway that has shown promising pre-clinical activity in several contexts of therapeutic resistant cancer.
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