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Articles by Cong He
Engineering an Implantable Bioartificial Pancreas to Balance Transport, Containment, and Retrieval
Disclosure ChatGPT (OpenAI) assisted in drafting and revising text, literature-verification summaries, and document formatting. ChatGPT image-generation tools assisted in the preparation of conceptual Figures 1 and 2. Figure 3 reproduces a published figure with attribution and was not AI-generated. No new experimental data were generated. This assistance is disclosed to the editor for explicit permission in accordance with journal policy.
TNF/TNFR1 axis restrains inflammation-suppressive myeloid subclusters to drive acute pancreatitis
Abstract Acute pancreatitis (AP) is a pancreatic inflammatory disorder that can progress to fatal systemic inflammation and multiorgan failure. Although tumor necrosis factor (TNF) signaling is a key regulator of inflammation, its contribution to AP progression and its therapeutic potential remain incompletely understood. We induced AP in wild-type and Tnfr1–/– mice using caerulein, pancreatic duct ligation, or L-arginine.
Orbital angular momentum multiplexing diffractive neural networks for high-capacity optical inference
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Abstract Deep diffractive neural networks have emerged as an all-optical computing paradigm that overcomes the bottlenecks of traditional electronic computing. However, traditional deep diffractive neural networks are typically limited to single-task processing. Here we demonstrate an orbital angular momentum multiplexing diffractive neural network (OAM-MDNN) that completes several recognition tasks simultaneously by exploiting orthogonal OAM modes to encode and decode information.
By Cong He, Xin Li Verified, Hongbo Wang, Jiaqin Li, Zian Zhang, Qiang Jiang, Nan Zhang Verified, Yongtian Wang, Lingling Huang, Shendong Liu
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Nature
Verified
Bifidobacterium Pseudolongum -Derived Acetate Attenuates Acute Pancreatitis Through GPR43-Mediated Suppression of M1 Macrophage Polarization
1 Introduction Acute pancreatitis (AP) is an inflammatory disorder characterized by the premature activation of trypsinogen, infiltration of inflammatory cells, and acinar cell death [1, 2]. Although most cases classified as mild AP (MAP) resolve spontaneously within a week, approximately 20% of patients progress to severe AP (SAP), a condition associated with mortality rates as high as 30% [3, 4]. Currently, an effective strategy to reduce mortality in patients with SAP is unavailable.
Diagnostic value of phenotypic testing combined with molecular biology testing for tuberculosis - Scientific Reports
Abstract To evaluate the diagnostic value of combining phenotypic testing with molecular biology testing for tuberculosis, a retrospective study was conducted on 264 presumed pulmonary tuberculosis patients across four hospitals from July 2021 to September 2023.
[2510.04952] Safe and Compliant Cross-Market Trade Execution via Constrained RL and Zero-Knowledge Audits
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Research Review of Comprehensive Treatment of Cushing's syndrome with | OTT
Back to Journals » OncoTargets and Therapy » Volume 19 Authors Chen B, He C , Han L, Wang H, Ma Y, Wang R, Cai X Received 2 October 2025 Accepted for publication 27 January 2026 Published 6 February 2026 Volume 2026:19 Pages 1—14 DOI https://doi.org/10.2147/OTT.S571776 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Sanjay Singh Baojiang Chen,1 Cong He,1 Lichao Han,1 Hejie Wang,2 Yijia Ma,1 Rui Wang,3 Xiaojun...
Evidence for single variant in altermagnetic RuO2(101) thin films - Nature Communications
Abstract Altermagnetism presents intriguing possibilities for spintronic devices due to its unique combination of strong spin-splitting and zero net magnetization. However, realizing its full potential hinges on fabricating single-variant altermagnetic thin films.
Trait‐Mediated Competition for Light Underpins Plant Diversity Loss Under Eutrophication
1 Introduction Anthropogenic activities, including intensified fertilizer use and fossil fuel combustion, have profoundly altered nitrogen and phosphorus cycles (Galloway et al. 2004, 2008; Peñuelas et al. 2012, 2013; Smil 2000). These changes increase nitrogen and phosphorus input into terrestrial ecosystems, enhancing plant biomass and highlighting their status as key limiting nutrients for primary production (Du et al. 2020; Elser et al. 2007; Harpole et al. 2016).
Effects of melatonin disorders on Parkinson's disease: a review of mec
Back to Journals » Neuropsychiatric Disease and Treatment » Volume 21 Authors Shen Y , He C , Wang Y, Zhang Y, Liu Z, Chen X, Wang S, Bai Y Received 23 May 2025 Accepted for publication 30 July 2025 Published 18 October 2025 Volume 2025:21 Pages 2335—2355 DOI https://doi.org/10.2147/NDT.S536997 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Taro Kishi Yiwei Shen,1,* Cong He,1,* Yulin Wang,1 Yu...
Integrating Genetic and Immune Profiles for Personalized Immunotherapy in Alzheimer’s Disease
Submitted: 11 January 2025 You are already at the latest version Alzheimer's disease is the leading cause of dementia worldwide, with the number of patients expected to reach 131 million by 2050. Current treatments can only alleviate the symptoms of AD and are unable to halt the progression of the disease. Personalized immunotherapy shows great potential, as it can improve treatment efficacy and reduce side effects through precise targeting and early intervention.
Analysis of Risk Factors for White-Centered Retinal Hemorrhage in Full
Back to Journals » International Journal of General Medicine » Volume 18 Original Research Infectious Diseases Authors He C, Liao Y, He X, Ye Z, Su S, Zhang Y Received 29 November 2024 Accepted for publication 8 March 2025 Published 27 March 2025 Volume 2025:18 Pages 1747—1756 DOI https://doi.org/10.2147/IJGM.S505664 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Prof.
Regulation of endotoxemia through the gut microbiota: The role of the Mediterranean diet and its components
CONFLICT OF INTEREST The authors declare that they have no conflict of interest. References 1, , , . Regulation of gut microbiota and metabolic endotoxemia with dietary factors. Nutrients. 2019; 11(10):2277. 2, . The importance of food for endotoxemia and an inflammatory response. Int J Mol Sci. 2021; 22(17):9562. 3, , . Host defenses against metabolic endotoxaemia and their impact on lipopolysaccharide detection. Int Rev Immunol. 2017; 36(3): 125–144. 4, , , , , , et al.
The Associations between Healthy Eating Patterns and Risk of Metabolic Dysfunction-Associated Steatotic Liver Disease: A Case-Control Study
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Modeling and Optimization of Container Drayage Problem with Empty Container Constraints across Multiple Inland Depots
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Metal‐Organic Framework Based Mucoadhesive Nanodrugs for Multifunction Helicobacter Pylori Targeted Eradication, Inflammation Regulation and Gut Flora Protection
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202308286-sup-0001-SuppMat.pdf1.6 MB Supporting Information References 1, , , , , , J Biomed Sci 2019, 26, 23. 2a) , , , , , , , , , , Clin. Gastroenterol. Hepatol. 2019, 17, 1991; b) , , , , , , , , Antioxidants (Basel) 2021, 10, 943. 3, , , , , Int. J. Mol. Sci. 2023, 24, 2895. 4, , , , , , , , , , , , , , , Gut 2022, 71, 1724. 5, , , , , ACS Appl. Mater. Interfaces 2020, 12, 54316.
Metal‐Organic Framework Based Mucoadhesive Nanodrugs for Multifunction Helicobacter Pylori Targeted Eradication, Inflammation Regulation and Gut Flora Protection
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202308286-sup-0001-SuppMat.pdf1.6 MB Supporting Information References 1, , , , , , J Biomed Sci 2019, 26, 23. 2a) , , , , , , , , , , Clin. Gastroenterol. Hepatol. 2019, 17, 1991; b) , , , , , , , , Antioxidants (Basel) 2021, 10, 943. 3, , , , , Int. J. Mol. Sci. 2023, 24, 2895. 4, , , , , , , , , , , , , , , Gut 2022, 71, 1724. 5, , , , , ACS Appl. Mater. Interfaces 2020, 12, 54316.
Research on the upgrade and maintenance method of apple soluble solids content models
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest. REFERENCES , , , & (2021). Prediction of olive ripening degree combining image analysis and FT-NIR spectroscopy for virgin olive oil optimisation. Food Control, 123, 107755. https://doi.org/10.1016/j.foodcont.2020.107755 , , , , , & (2020). Towards fruit maturity estimation using NIR spectroscopy. Infrared Physics& Technology, 111, 103479. https://doi.org/10.1016/j.infrared.2020.103479 , , , , , & (2021).
The Prognostic and Immune Significance of CILP2 in Pan-Cancer and Its Relationship with the Progression of Pancreatic Cancer
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Research trends on the relationship between Helicobacter pylori and microbiota: A bibliometric analysis
Increasing evidence has indicated that Helicobacter pylori infection is associated with the complex microbiota in the digestive tract of the human body. We aimed to assess the research trends and hotspots in the field of H. pylori and microbiota using a quantitative method. The clinical studies on H. pylori and microbiota published from 2001 to 2022 were extracted from the Web of Science database.
IJMS | Free Full-Text | Unleashing the Potential of EIL Transcription Factors in Enhancing Sweet Orange Resistance to Bacterial Pathologies: Genome-Wide Identification and Expression Profiling
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A nomogram based on radiomics intermuscular adipose analysis to indicate arteriosclerosis in patients with newly diagnosed type 2 diabetes
Cong He, Dong Xie, Lin-feng Fu, Jin-na Yu, Fang-ye Wu, Yong-gang Qiu and Hong-wei Xu* Department of Radiology, Shaoxing Second Hospital, Shaoxing, Zhejiang, China Objective: Early identifying arteriosclerosis in newly diagnosed type 2 diabetes (T2D) patients could contribute to choosing proper subjects for early prevention.
Spin-torque generation using a compositional gradient at the interface between titanium and tungsten thin films
Abstract We experimentally demonstrate spin-torque generation using a compositional gradient at the interface between titanium and tungsten thin films. The width of the compositional gradient interface (CGI) between films is varied from 1.4 to 2.0 nm via sputtering. Spin-torque ferromagnetic resonance is observed in the ferromagnetic Ni95Cu5 alloy fabricated on a Ti/W bilayer with the CGI.
Incidence and affecting factors of pulmonary diffusing capacity impairment with COVID-19 survivors 18 months after discharge in Wuhan, China
Highlights • To evaluate the incidence of pulmonary diffusing capacity impairment (PDCI) and the affecting factors in clinical practice of COVID-19 patients 18 months after discharge.
Incidence and affecting factors of pulmonary diffusing capacity impairment with COVID-19 survivors 18 months after discharge in Wuhan, China
Dear Editor . The convalescent patients with COVID-19 have manifested particularly noticeable pulmonary diffusing capacity impairment (PDCI) Studies have showed that long-term sequelae from COVID-19 may affect human respiratory system, cardiovascular system, nervous system, immune system etc. with a negative impact on the patients’ mental health, well-being and quality of life, but the lungs are the organ most likely to sustain serious impairment from COVID-19 , .
Purinergic Receptor P2Y6 Is a Negative Regulator of NK Cell Maturation and Function
Zhenlong Li, Yaoxin Gao, Cong He, Huan Wei, Jiang Zhang, Hongmei Zhang, Lulu Hu and Wenzheng Jiang J Immunol September 15, 2021, 207 (6) 1555-1565; DOI: https://doi.org/10.4049/jimmunol.2000750 Key Points P2Y6 deficiency enhances the maturation and functions of NK cells. P2Y6 deficiency promotes the expression of T-bet in NK cells. P2Y6 deficiency increases the antitumor activities of NK cells.
Purinergic Receptor P2Y6 Is a Negative Regulator of NK Cell Maturation and Function
Zhenlong Li, Yaoxin Gao, Cong He, Huan Wei, Jiang Zhang, Hongmei Zhang, Lulu Hu and Wenzheng Jiang J Immunol August 23, 2021, ji2000750; DOI: https://doi.org/10.4049/jimmunol.2000750 Key Points P2Y6 deficiency enhances the maturation and functions of NK cells. P2Y6 deficiency promotes the expression of T-bet in NK cells. P2Y6 deficiency increases the antitumor activities of NK cells.
Unusual solute segregation phenomenon in coherent twin boundaries
Abstract Interface segregation of solute atoms has a profound effect on properties of engineering alloys.
P2Y6 Deficiency Enhances Dendritic Cell-Mediated Th1/Th17 Differentiation and Aggravates Experimental Autoimmune Encephalomyelitis
Zhenlong Li, Cong He, Jiang Zhang, Hongmei Zhang, Huan Wei, Shijia Wu and Wenzheng Jiang J Immunol July 15, 2020, 205 (2) 387-397; DOI: https://doi.org/10.4049/jimmunol.1900916 Key Points P2Y6 deficiency enhances DC-mediated Th1/Th17 differentiation. P2Y6 deficiency aggravates the pathogenesis of EAE. Abstract Dendritic cells (DCs) are essential APCs and play a crucial role in initiating and regulating the adaptive immune response.
P2Y6 Deficiency Enhances Dendritic Cell-Mediated Th1/Th17 Differentiation and Aggravates Experimental Autoimmune Encephalomyelitis
Zhenlong Li, Cong He, Jiang Zhang, Hongmei Zhang, Huan Wei, Shijia Wu and Wenzheng Jiang J Immunol June 17, 2020, ji1900916; DOI: https://doi.org/10.4049/jimmunol.1900916 Key Points P2Y6 deficiency enhances DC-mediated Th1/Th17 differentiation. P2Y6 deficiency aggravates the pathogenesis of EAE. Abstract Dendritic cells (DCs) are essential APCs and play a crucial role in initiating and regulating the adaptive immune response.
Letter: are microbes other than Helicobacter pylori associated with gastric cancer?
LETTERS TO THE EDITORS Nonghua Lu Corresponding Author E-mail address: lunonghua@ncu.edu.cn https://orcid.org/0000-0003-4373-551X Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China Search for more papers by this author Abstract LINKED CONTENT This article is linked to Gantuya et al papers. To view these articles, visit https://doi.org/10.1111/apt.15675 and https://doi.org/10.1111/apt.15757.
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